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A two-phase procedure for non-normal quantitative trait genetic association study

BACKGROUND: The nonparametric trend test (NPT) is well suitable for identifying the genetic variants associated with quantitative traits when the trait values do not satisfy the normal distribution assumption. If the genetic model, defined according to the mode of inheritance, is known, the NPT deri...

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Detalles Bibliográficos
Autores principales: Zhang, Wei, Li, Huiyun, Li, Zhaohai, Li, Qizhai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4730615/
https://www.ncbi.nlm.nih.gov/pubmed/26821800
http://dx.doi.org/10.1186/s12859-016-0888-x