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A two-phase procedure for non-normal quantitative trait genetic association study
BACKGROUND: The nonparametric trend test (NPT) is well suitable for identifying the genetic variants associated with quantitative traits when the trait values do not satisfy the normal distribution assumption. If the genetic model, defined according to the mode of inheritance, is known, the NPT deri...
Autores principales: | Zhang, Wei, Li, Huiyun, Li, Zhaohai, Li, Qizhai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4730615/ https://www.ncbi.nlm.nih.gov/pubmed/26821800 http://dx.doi.org/10.1186/s12859-016-0888-x |
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