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The fibroblast Tiam1-osteopontin pathway modulates breast cancer invasion and metastasis
BACKGROUND: The tumor microenvironment has complex effects in cancer pathophysiology that are not fully understood. Most cancer therapies are directed against malignant cells specifically, leaving pro-malignant signals from the microenvironment unaddressed. Defining specific mechanisms by which the...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4730665/ https://www.ncbi.nlm.nih.gov/pubmed/26821678 http://dx.doi.org/10.1186/s13058-016-0674-8 |