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Mechanisms of murine cerebral malaria: Multimodal imaging of altered cerebral metabolism and protein oxidation at hemorrhage sites
Using a multimodal biospectroscopic approach, we settle several long-standing controversies over the molecular mechanisms that lead to brain damage in cerebral malaria, which is a major health concern in developing countries because of high levels of mortality and permanent brain damage. Our results...
Autores principales: | Hackett, Mark J., Aitken, Jade B., El-Assaad, Fatima, McQuillan, James A., Carter, Elizabeth A., Ball, Helen J., Tobin, Mark J., Paterson, David, de Jonge, Martin D., Siegele, Rainer, Cohen, David D., Vogt, Stefan, Grau, Georges E., Hunt, Nicholas H., Lay, Peter A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4730848/ https://www.ncbi.nlm.nih.gov/pubmed/26824064 http://dx.doi.org/10.1126/sciadv.1500911 |
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