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Dual Effects of Bisphosphonates on Ectopic Skin and Vascular Soft Tissue Mineralization versus Bone Microarchitecture in a Mouse Model of Generalized Arterial Calcification of Infancy

Generalized arterial calcification of infancy (GACI) is an intractable ectopic mineralization disorder caused by mutations in the ENPP1 gene resulting in reduced plasma inorganic pyrophosphate levels. We previously characterized the Enpp1(asj) mutant mouse as a model of GACI, and we have now explore...

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Detalles Bibliográficos
Autores principales:	Li, Qiaoli, Kingman, Joshua, Sundberg, John P., Levine, Michael A., Uitto, Jouni
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4731049/ https://www.ncbi.nlm.nih.gov/pubmed/26763447 http://dx.doi.org/10.1038/JID.2015.377

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