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Designing malaria vaccines to circumvent antigen variability()

Prospects for malaria eradication will be greatly enhanced by an effective vaccine, but parasite genetic diversity poses a major impediment to malaria vaccine efficacy. In recent pre-clinical and field trials, vaccines based on polymorphic Plasmodium falciparum antigens have shown efficacy only agai...

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Detalles Bibliográficos
Autores principales: Ouattara, Amed, Barry, Alyssa E., Dutta, Sheetij, Remarque, Edmond J., Beeson, James G., Plowe, Christopher V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4731100/
https://www.ncbi.nlm.nih.gov/pubmed/26475447
http://dx.doi.org/10.1016/j.vaccine.2015.09.110