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Mutations in Mtr4 Structural Domains Reveal Their Important Role in Regulating tRNA(i)(Met) Turnover in Saccharomyces cerevisiae and Mtr4p Enzymatic Activities In Vitro
RNA processing and turnover play important roles in the maturation, metabolism and quality control of a large variety of RNAs thereby contributing to gene expression and cellular health. The TRAMP complex, composed of Air2p, Trf4p and Mtr4p, stimulates nuclear exosome-dependent RNA processing and de...
Autores principales: | Li, Yan, Burclaff, Joseph, Anderson, James T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4731217/ https://www.ncbi.nlm.nih.gov/pubmed/26820724 http://dx.doi.org/10.1371/journal.pone.0148090 |
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