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Failed Endotracheal Intubation and Adverse Outcomes Among Extremely Low Birth Weight Infants
OBJECTIVE: To quantify the importance of successful endotracheal intubation on the first attempt among extremely low birth weight (ELBW) infants who require resuscitation after delivery. STUDY DESIGN: A retrospective chart review was conducted for all ELBW infants ≤1000 g born between January 2007 a...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4731260/ https://www.ncbi.nlm.nih.gov/pubmed/26540244 http://dx.doi.org/10.1038/jp.2015.158 |
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author | Wallenstein, Matthew B. Birnie, Krista L. Arain, Yassar H. Yang, Wei Yamada, Nicole K. Huffman, Lynne C. Palma, Jonathan P. Chock, Valerie Y. Shaw, Gary M. Stevenson, David K. |
author_facet | Wallenstein, Matthew B. Birnie, Krista L. Arain, Yassar H. Yang, Wei Yamada, Nicole K. Huffman, Lynne C. Palma, Jonathan P. Chock, Valerie Y. Shaw, Gary M. Stevenson, David K. |
author_sort | Wallenstein, Matthew B. |
collection | PubMed |
description | OBJECTIVE: To quantify the importance of successful endotracheal intubation on the first attempt among extremely low birth weight (ELBW) infants who require resuscitation after delivery. STUDY DESIGN: A retrospective chart review was conducted for all ELBW infants ≤1000 g born between January 2007 and May 2014 at a level IV neonatal intensive care unit. Infants were included if intubation was attempted during the first five minutes of life, or if intubation was attempted during the first 10 minutes of life with heart rate < 100. The primary outcome was death or neurodevelopmental impairment. The association between successful intubation on the first attempt and the primary outcome was assessed using multivariable logistic regression with adjustment for birth weight, gestational age, gender, and antenatal steroids. RESULTS: The study sample included 88 ELBW infants. Forty-percent were intubated on the first attempt and 60% required multiple intubation attempts. Death or neurodevelopmental impairment occurred in 29% of infants intubated on the first attempt, compared to 53% of infants that required multiple attempts, adjusted odds ratio 0.4 (95% confidence interval 0.1 - 1.0), p < 0.05. CONCLUSION: Successful intubation on the first attempt is associated with improved neurodevelopmental outcomes among ELBW infants. This study confirms the importance of rapid establishment of a stable airway in ELBW infants requiring resuscitation after birth and has implications for personnel selection and role assignment in the delivery room. |
format | Online Article Text |
id | pubmed-4731260 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
record_format | MEDLINE/PubMed |
spelling | pubmed-47312602016-08-01 Failed Endotracheal Intubation and Adverse Outcomes Among Extremely Low Birth Weight Infants Wallenstein, Matthew B. Birnie, Krista L. Arain, Yassar H. Yang, Wei Yamada, Nicole K. Huffman, Lynne C. Palma, Jonathan P. Chock, Valerie Y. Shaw, Gary M. Stevenson, David K. J Perinatol Article OBJECTIVE: To quantify the importance of successful endotracheal intubation on the first attempt among extremely low birth weight (ELBW) infants who require resuscitation after delivery. STUDY DESIGN: A retrospective chart review was conducted for all ELBW infants ≤1000 g born between January 2007 and May 2014 at a level IV neonatal intensive care unit. Infants were included if intubation was attempted during the first five minutes of life, or if intubation was attempted during the first 10 minutes of life with heart rate < 100. The primary outcome was death or neurodevelopmental impairment. The association between successful intubation on the first attempt and the primary outcome was assessed using multivariable logistic regression with adjustment for birth weight, gestational age, gender, and antenatal steroids. RESULTS: The study sample included 88 ELBW infants. Forty-percent were intubated on the first attempt and 60% required multiple intubation attempts. Death or neurodevelopmental impairment occurred in 29% of infants intubated on the first attempt, compared to 53% of infants that required multiple attempts, adjusted odds ratio 0.4 (95% confidence interval 0.1 - 1.0), p < 0.05. CONCLUSION: Successful intubation on the first attempt is associated with improved neurodevelopmental outcomes among ELBW infants. This study confirms the importance of rapid establishment of a stable airway in ELBW infants requiring resuscitation after birth and has implications for personnel selection and role assignment in the delivery room. 2015-11-05 2016-02 /pmc/articles/PMC4731260/ /pubmed/26540244 http://dx.doi.org/10.1038/jp.2015.158 Text en http://www.nature.com/authors/editorial_policies/license.html#terms Users may view, print, copy, and download text and data-mine the content in such documents, for the purposes of academic research, subject always to the full Conditions of use:http://www.nature.com/authors/editorial_policies/license.html#terms |
spellingShingle | Article Wallenstein, Matthew B. Birnie, Krista L. Arain, Yassar H. Yang, Wei Yamada, Nicole K. Huffman, Lynne C. Palma, Jonathan P. Chock, Valerie Y. Shaw, Gary M. Stevenson, David K. Failed Endotracheal Intubation and Adverse Outcomes Among Extremely Low Birth Weight Infants |
title | Failed Endotracheal Intubation and Adverse Outcomes Among Extremely Low Birth Weight Infants |
title_full | Failed Endotracheal Intubation and Adverse Outcomes Among Extremely Low Birth Weight Infants |
title_fullStr | Failed Endotracheal Intubation and Adverse Outcomes Among Extremely Low Birth Weight Infants |
title_full_unstemmed | Failed Endotracheal Intubation and Adverse Outcomes Among Extremely Low Birth Weight Infants |
title_short | Failed Endotracheal Intubation and Adverse Outcomes Among Extremely Low Birth Weight Infants |
title_sort | failed endotracheal intubation and adverse outcomes among extremely low birth weight infants |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4731260/ https://www.ncbi.nlm.nih.gov/pubmed/26540244 http://dx.doi.org/10.1038/jp.2015.158 |
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