Cargando…

A20 Deficiency in Lung Epithelial Cells Protects against Influenza A Virus Infection

A20 negatively regulates multiple inflammatory signalling pathways. We here addressed the role of A20 in club cells (also known as Clara cells) of the bronchial epithelium in their response to influenza A virus infection. Club cells provide a niche for influenza virus replication, but little is know...

Descripción completa

Detalles Bibliográficos
Autores principales:	Maelfait, Jonathan, Roose, Kenny, Vereecke, Lars, Mc Guire, Conor, Sze, Mozes, Schuijs, Martijn J., Willart, Monique, Itati Ibañez, Lorena, Hammad, Hamida, Lambrecht, Bart N., Beyaert, Rudi, Saelens, Xavier, van Loo, Geert
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4731390/ https://www.ncbi.nlm.nih.gov/pubmed/26815999 http://dx.doi.org/10.1371/journal.ppat.1005410

Ejemplares similares

A20 (Tnfaip3) Deficiency in Myeloid Cells Protects against Influenza A Virus Infection
por: Maelfait, Jonathan, et al.
Publicado: (2012)

Correction: A20 (Tnfaip3) Deficiency in Myeloid Cells Protects against Influenza A Virus Infection
por: Maelfait, Jonathan, et al.
Publicado: (2012)

Enterocyte-specific A20 deficiency sensitizes to tumor necrosis factor–induced toxicity and experimental colitis
por: Vereecke, Lars, et al.
Publicado: (2010)

Interleukin-1α controls allergic sensitization to inhaled house dust mite via the epithelial release of GM-CSF and IL-33
por: Willart, Monique A.M., et al.
Publicado: (2012)

A20-Deficient Mast Cells Exacerbate Inflammatory Responses In Vivo
por: Heger, Klaus, et al.
Publicado: (2014)

NKT sublineage specification and survival requires the ubiquitin-modifying enzyme TNFAIP3/A20
por: Drennan, Michael B., et al.
Publicado: (2016)

Protection against Influenza A Virus Challenge with M2e-Displaying Filamentous Escherichia coli Phages
por: Deng, Lei, et al.
Publicado: (2015)

Inflammatory dendritic cells—not basophils—are necessary and sufficient for induction of Th2 immunity to inhaled house dust mite allergen
por: Hammad, Hamida, et al.
Publicado: (2010)

Controlling Influenza by Cytotoxic T-Cells: Calling for Help from Destroyers
por: Schotsaert, Michael, et al.
Publicado: (2010)

M2e-Displaying Virus-Like Particles with Associated RNA Promote T Helper 1 Type Adaptive Immunity against Influenza A
por: Ibañez, Lorena Itatí, et al.
Publicado: (2013)

Essential Role of Lung Plasmacytoid Dendritic Cells in Preventing Asthmatic Reactions to Harmless Inhaled Antigen
por: de Heer, Hendrik Jan, et al.
Publicado: (2004)

Airway epithelial cell necroptosis contributes to asthma exacerbation in a mouse model of house dust mite-induced allergic inflammation
por: Oikonomou, Nikos, et al.
Publicado: (2021)

Negative regulation of NF-κB and its involvement in rheumatoid arthritis
por: van Loo, Geert, et al.
Publicado: (2011)

Alum adjuvant boosts adaptive immunity by inducing uric acid and activating inflammatory dendritic cells
por: Kool, Mirjam, et al.
Publicado: (2008)

Imaging regulatory T cell dynamics and suppression of T cell priming mediated by CTLA4
por: Matheu, Melanie P., et al.
Publicado: (2015)

The lung vascular filter as a site of immune induction for T cell responses to large embolic antigen
por: Willart, Monique A.M., et al.
Publicado: (2009)

Reduced protection of RIPK3-deficient mice against influenza by matrix protein 2 ectodomain targeted active and passive vaccination strategies
por: Oltean, Teodora, et al.
Publicado: (2022)

A20 prevents chronic liver inflammation and cancer by protecting hepatocytes from death
por: Catrysse, L, et al.
Publicado: (2016)

TLR4 signalling in pulmonary stromal cells is critical for inflammation and immunity in the airways
por: Perros, Frederic, et al.
Publicado: (2011)

Cellular networks controlling Th2 polarization in allergy and immunity
por: Kool, Mirjam, et al.
Publicado: (2012)

The Mucosal Adjuvant Cholera Toxin B Instructs Non-Mucosal Dendritic Cells to Promote IgA Production Via Retinoic Acid and TGF-β
por: Gloudemans, Anouk K., et al.
Publicado: (2013)

Pharmacological inhibition of MALT1 protease activity protects mice in a mouse model of multiple sclerosis
por: Mc Guire, Conor, et al.
Publicado: (2014)

Stimulation of Toll-like receptor 3 and 4 induces interleukin-1β maturation by caspase-8
por: Maelfait, Jonathan, et al.
Publicado: (2008)

Influenza and Memory T Cells: How to Awake the Force
por: Spitaels, Jan, et al.
Publicado: (2016)

OTULIN protects the intestinal epithelium from apoptosis during inflammation and infection
por: Verboom, Lien, et al.
Publicado: (2023)

The hygiene hypothesis: immunological mechanisms of airway tolerance
por: Haspeslagh, Eline, et al.
Publicado: (2018)

Inflammatory monocytes regulate Th1 oriented immunity to CpG adjuvanted protein vaccines through production of IL-12
por: De Koker, S., et al.
Publicado: (2017)

Tnfaip3 expression in pulmonary conventional type 1 Langerin‐expressing dendritic cells regulates T helper 2‐mediated airway inflammation in mice
por: Vroman, Heleen, et al.
Publicado: (2020)

Structure and antagonism of the receptor complex mediated by human TSLP in allergy and asthma
por: Verstraete, Kenneth, et al.
Publicado: (2017)

The ubiquitin editing enzyme A20 (TNFAIP3) is upregulated during permanent middle cerebral artery occlusion but does not influence disease outcome
por: Mc Guire, C, et al.
Publicado: (2013)

Physical and functional interaction between A20 and ATG16L1-WD40 domain in the control of intestinal homeostasis
por: Slowicka, Karolina, et al.
Publicado: (2019)

Early IL-1 Signaling Promotes iBALT Induction after Influenza Virus Infection
por: Neyt, Katrijn, et al.
Publicado: (2016)

Tertiary lymphoid organs in infection and autoimmunity
por: Neyt, Katrijn, et al.
Publicado: (2012)

In vivo depletion of lung CD11c(+) dendritic cells during allergen challenge abrogates the characteristic features of asthma
por: van Rijt, Leonie S., et al.
Publicado: (2005)

Evidence for local dendritic cell activation in pulmonary sarcoidosis
por: Berge, Bregje Ten, et al.
Publicado: (2012)

Negative regulation of the NLRP3 inflammasome by A20 protects against arthritis
por: Walle, Lieselotte Vande, et al.
Publicado: (2014)

Dendritic cells are crucial for maintenance of tertiary lymphoid structures in the lung of influenza virus–infected mice
por: GeurtsvanKessel, Corine H., et al.
Publicado: (2009)

Isolated Schistosoma mansoni eggs prevent allergic airway inflammation
por: Obieglo, Katja, et al.
Publicado: (2018)

A20 deficiency sensitizes pancreatic beta cells to cytokine-induced apoptosis in vitro but does not influence type 1 diabetes development in vivo
por: Catrysse, L, et al.
Publicado: (2015)

Inhibition of Caspases Increases the Sensitivity of L929 Cells to Necrosis Mediated by Tumor Necrosis Factor
por: Vercammen, Dominique, et al.
Publicado: (1998)

Cannot write session to /tmp/vufind_sessions/sess_nf3u6f6v8ah7qaak6vs28him8k