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Childhood allergic bronchopulmonary aspergillosis presenting as a middle lobe syndrome
Allergic bronchopulmonary aspergillosis (ABPA) is infrequently documented in children with asthma. Although collapse is not uncommon, middle lobe syndrome (MLS) as a presentation of ABPA is rather a rarity. A 9-year-old female child with asthma presented with increase in intensity of symptoms along...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Asia Pacific Association of Allergy, Asthma and Clinical Immunology
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4731483/ https://www.ncbi.nlm.nih.gov/pubmed/26844222 http://dx.doi.org/10.5415/apallergy.2016.6.1.67 |
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author | Shah, Ashok Gera, Kamal Panjabi, Chandramani |
author_facet | Shah, Ashok Gera, Kamal Panjabi, Chandramani |
author_sort | Shah, Ashok |
collection | PubMed |
description | Allergic bronchopulmonary aspergillosis (ABPA) is infrequently documented in children with asthma. Although collapse is not uncommon, middle lobe syndrome (MLS) as a presentation of ABPA is rather a rarity. A 9-year-old female child with asthma presented with increase in intensity of symptoms along with a right midzone patchy consolidation on a chest radiograph. In addition, an ill-defined opacity abutting the right cardiac border with loss of cardiac silhouette was noted. A right lateral view confirmed a MLS, which was further corroborated by high resolution computed tomography. Central bronchiectasis was also observed, which prompted a work-up for ABPA. The child met 7/8 major diagnostic criteria for ABPA. She was then initiated on oral prednisolone that resulted in a marked clinical improvement within a fortnight. Radiological clearance occurred at 3 months with inflation of the middle lobe. ABPA presenting with MLS in a child is yet to be reported. A high index of suspicion is required to establish the diagnosis of ABPA in a child presenting with MLS. This would obviate the invasive investigations usually done to ascertain the cause of MLS. |
format | Online Article Text |
id | pubmed-4731483 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Asia Pacific Association of Allergy, Asthma and Clinical Immunology |
record_format | MEDLINE/PubMed |
spelling | pubmed-47314832016-02-03 Childhood allergic bronchopulmonary aspergillosis presenting as a middle lobe syndrome Shah, Ashok Gera, Kamal Panjabi, Chandramani Asia Pac Allergy Educational & Teaching Material Allergic bronchopulmonary aspergillosis (ABPA) is infrequently documented in children with asthma. Although collapse is not uncommon, middle lobe syndrome (MLS) as a presentation of ABPA is rather a rarity. A 9-year-old female child with asthma presented with increase in intensity of symptoms along with a right midzone patchy consolidation on a chest radiograph. In addition, an ill-defined opacity abutting the right cardiac border with loss of cardiac silhouette was noted. A right lateral view confirmed a MLS, which was further corroborated by high resolution computed tomography. Central bronchiectasis was also observed, which prompted a work-up for ABPA. The child met 7/8 major diagnostic criteria for ABPA. She was then initiated on oral prednisolone that resulted in a marked clinical improvement within a fortnight. Radiological clearance occurred at 3 months with inflation of the middle lobe. ABPA presenting with MLS in a child is yet to be reported. A high index of suspicion is required to establish the diagnosis of ABPA in a child presenting with MLS. This would obviate the invasive investigations usually done to ascertain the cause of MLS. Asia Pacific Association of Allergy, Asthma and Clinical Immunology 2016-01 2016-01-27 /pmc/articles/PMC4731483/ /pubmed/26844222 http://dx.doi.org/10.5415/apallergy.2016.6.1.67 Text en Copyright © 2016. Asia Pacific Association of Allergy, Asthma and Clinical Immunology. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Educational & Teaching Material Shah, Ashok Gera, Kamal Panjabi, Chandramani Childhood allergic bronchopulmonary aspergillosis presenting as a middle lobe syndrome |
title | Childhood allergic bronchopulmonary aspergillosis presenting as a middle lobe syndrome |
title_full | Childhood allergic bronchopulmonary aspergillosis presenting as a middle lobe syndrome |
title_fullStr | Childhood allergic bronchopulmonary aspergillosis presenting as a middle lobe syndrome |
title_full_unstemmed | Childhood allergic bronchopulmonary aspergillosis presenting as a middle lobe syndrome |
title_short | Childhood allergic bronchopulmonary aspergillosis presenting as a middle lobe syndrome |
title_sort | childhood allergic bronchopulmonary aspergillosis presenting as a middle lobe syndrome |
topic | Educational & Teaching Material |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4731483/ https://www.ncbi.nlm.nih.gov/pubmed/26844222 http://dx.doi.org/10.5415/apallergy.2016.6.1.67 |
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