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IGF-Binding Proteins in Type-1 Diabetes Are More Severely Altered in the Presence of Complications
AIMS: Reduced levels of free and total insulin-like growth factor 1 (IGF-I) have been observed in type-1 diabetes (T1D) patients. The bioavailability of IGF-I from the circulation to the target cells is controlled by multifunctional IGF-binding proteins (IGFBPs). The aim of this study was to profile...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4731488/ https://www.ncbi.nlm.nih.gov/pubmed/26858687 http://dx.doi.org/10.3389/fendo.2016.00002 |