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Hepatocyte TRAF3 promotes insulin resistance and type 2 diabetes in mice with obesity

OBJECTIVE: Metabolic inflammation is believed to promote insulin resistance and type 2 diabetes progression in obesity. TRAF3, a cytoplasmic signaling protein, has been known to mediate/modulate cytokine signaling in immune cells. The goal is to define the metabolic function of hepatic TRAF3 in the...

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Detalles Bibliográficos
Autores principales:	Chen, Zheng, Canet, Mark J., Sheng, Liang, Jiang, Lin, Xiong, Yi, Yin, Lei, Rui, Liangyou
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2015
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4731737/ https://www.ncbi.nlm.nih.gov/pubmed/26909311 http://dx.doi.org/10.1016/j.molmet.2015.09.013

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