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Conformational Dynamics, Ligand Binding and Effects of Mutations in NirE an S-Adenosyl-L-Methionine Dependent Methyltransferase

Heme d1, a vital tetrapyrrol involved in the denitrification processes is synthesized from its precursor molecule precorrin-2 in a chemical reaction catalysed by an S-adenosyl-L-methionine (SAM) dependent Methyltransferase (NirE). The NirE enzyme catalyses the transfer of a methyl group from the SAM...

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Detalles Bibliográficos
Autores principales:	Singh, Warispreet, Karabencheva-Christova, Tatyana G., Black, Gary W., Ainsley, Jon, Dover, Lynn, Christov, Christo Z.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4731766/ https://www.ncbi.nlm.nih.gov/pubmed/26822701 http://dx.doi.org/10.1038/srep20107

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