Uricase alkaline enzymosomes with enhanced stabilities and anti-hyperuricemia effects induced by favorable microenvironmental changes

Enzyme therapy is an effective strategy to treat diseases. Three strategies were pursued to provide the favorable microenvironments for uricase (UCU) to eventually improve its features: using the right type of buffer to constitute the liquid media where catalyze reactions take place; entrapping UCU...

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Detalles Bibliográficos
Autores principales: Zhou, Yunli, Zhang, Mi, He, Dan, Hu, Xueyuan, Xiong, Huarong, Wu, Jianyong, Zhu, Biyue, Zhang, Jingqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4731772/
https://www.ncbi.nlm.nih.gov/pubmed/26823332
http://dx.doi.org/10.1038/srep20136

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4731772/
https://www.ncbi.nlm.nih.gov/pubmed/26823332
http://dx.doi.org/10.1038/srep20136

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