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Allosteric Pathways in the PPARγ-RXRα nuclear receptor complex

Understanding the nature of allostery in DNA-nuclear receptor (NR) complexes is of fundamental importance for drug development since NRs regulate the transcription of a myriad of genes in humans and other metazoans. Here, we investigate allostery in the peroxisome proliferator-activated/retinoid X r...

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Detalles Bibliográficos
Autores principales:	Ricci, Clarisse G., Silveira, Rodrigo L., Rivalta, Ivan, Batista, Victor S., Skaf, Munir S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4731802/ https://www.ncbi.nlm.nih.gov/pubmed/26823026 http://dx.doi.org/10.1038/srep19940

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