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High levels of cathepsin D and cystatin B are associated with increased risk of coronary events

OBJECTIVE: The majority of acute coronary syndromes are caused by plaque ruptures. Proteases secreted by macrophages play an important role in plaque ruptures by degrading extracellular matrix proteins in the fibrous cap. Matrix metalloproteinases have been shown to be markers for cardiovascular dis...

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Detalles Bibliográficos
Autores principales: Gonçalves, Isabel, Hultman, Karin, Dunér, Pontus, Edsfeldt, Andreas, Hedblad, Bo, Fredrikson, Gunilla Nordin, Björkbacka, Harry, Nilsson, Jan, Bengtsson, Eva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4731836/
https://www.ncbi.nlm.nih.gov/pubmed/26848396
http://dx.doi.org/10.1136/openhrt-2015-000353