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High levels of cathepsin D and cystatin B are associated with increased risk of coronary events
OBJECTIVE: The majority of acute coronary syndromes are caused by plaque ruptures. Proteases secreted by macrophages play an important role in plaque ruptures by degrading extracellular matrix proteins in the fibrous cap. Matrix metalloproteinases have been shown to be markers for cardiovascular dis...
Autores principales: | Gonçalves, Isabel, Hultman, Karin, Dunér, Pontus, Edsfeldt, Andreas, Hedblad, Bo, Fredrikson, Gunilla Nordin, Björkbacka, Harry, Nilsson, Jan, Bengtsson, Eva |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4731836/ https://www.ncbi.nlm.nih.gov/pubmed/26848396 http://dx.doi.org/10.1136/openhrt-2015-000353 |
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