Chinese herbal medicines as a source of molecules with anti-enterovirus 71 activity

Enterovirus 71 (EV71) is one of the causative agents of hand, foot, and mouth disease (HFMD), which sometimes leads to severe neurological disease and death in the Asia–Pacific region. In Chinese medicine, HFMD is caused mainly by an accumulation of damp-heat and toxicity in the body. No effective d...

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Detalles Bibliográficos
Autores principales: Wang, Mengjie, Tao, Ling, Xu, Hongxi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4731985/
https://www.ncbi.nlm.nih.gov/pubmed/26834824
http://dx.doi.org/10.1186/s13020-016-0074-0
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author Wang, Mengjie
Tao, Ling
Xu, Hongxi
author_facet Wang, Mengjie
Tao, Ling
Xu, Hongxi
author_sort Wang, Mengjie
collection PubMed
description Enterovirus 71 (EV71) is one of the causative agents of hand, foot, and mouth disease (HFMD), which sometimes leads to severe neurological disease and death in the Asia–Pacific region. In Chinese medicine, HFMD is caused mainly by an accumulation of damp-heat and toxicity in the body. No effective drugs are currently available for the treatment and prevention of EV71 infection. This review summarizes the potential Chinese herbal extracts and isolated compounds with antiviral activity against EV71 and their clinical applications, especially those categorized as heat-clearing and detoxifying.
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spelling pubmed-47319852016-01-30 Chinese herbal medicines as a source of molecules with anti-enterovirus 71 activity Wang, Mengjie Tao, Ling Xu, Hongxi Chin Med Review Enterovirus 71 (EV71) is one of the causative agents of hand, foot, and mouth disease (HFMD), which sometimes leads to severe neurological disease and death in the Asia–Pacific region. In Chinese medicine, HFMD is caused mainly by an accumulation of damp-heat and toxicity in the body. No effective drugs are currently available for the treatment and prevention of EV71 infection. This review summarizes the potential Chinese herbal extracts and isolated compounds with antiviral activity against EV71 and their clinical applications, especially those categorized as heat-clearing and detoxifying. BioMed Central 2016-01-28 /pmc/articles/PMC4731985/ /pubmed/26834824 http://dx.doi.org/10.1186/s13020-016-0074-0 Text en © Wang et al. 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Review
Wang, Mengjie
Tao, Ling
Xu, Hongxi
Chinese herbal medicines as a source of molecules with anti-enterovirus 71 activity
title Chinese herbal medicines as a source of molecules with anti-enterovirus 71 activity
title_full Chinese herbal medicines as a source of molecules with anti-enterovirus 71 activity
title_fullStr Chinese herbal medicines as a source of molecules with anti-enterovirus 71 activity
title_full_unstemmed Chinese herbal medicines as a source of molecules with anti-enterovirus 71 activity
title_short Chinese herbal medicines as a source of molecules with anti-enterovirus 71 activity
title_sort chinese herbal medicines as a source of molecules with anti-enterovirus 71 activity
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4731985/
https://www.ncbi.nlm.nih.gov/pubmed/26834824
http://dx.doi.org/10.1186/s13020-016-0074-0
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