Complement component C3a plays a critical role in endothelial activation and leukocyte recruitment into the brain

BACKGROUND: The complement system is becoming increasingly recognized as a key participant in many neurodegenerative diseases of the brain. Complement-deficient animals exhibit reduced neuroinflammation. METHODS: In the present study, we administered intracerebroventricularly lipopolysaccharide (LPS...

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Detalles Bibliográficos
Autores principales: Wu, Fengjiao, Zou, Qiang, Ding, Xiaodan, Shi, Dongyan, Zhu, Xingxing, Hu, Weiguo, Liu, Lixin, Zhou, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4731990/
https://www.ncbi.nlm.nih.gov/pubmed/26822321
http://dx.doi.org/10.1186/s12974-016-0485-y

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