Lipidomics and H(2)(18)O labeling techniques reveal increased remodeling of DHA-containing membrane phospholipids associated with abnormal locomotor responses in α-tocopherol deficient zebrafish (danio rerio) embryos

We hypothesized that vitamin E (α-tocopherol) is required by the developing embryonic brain to prevent depletion of highly polyunsaturated fatty acids, especially docosahexaenoic acid (DHA, 22:6), the loss of which we predicted would underlie abnormal morphological and behavioral outcomes. Therefore...

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Detalles Bibliográficos
Autores principales: McDougall, Melissa Q., Choi, Jaewoo, Stevens, Jan F., Truong, Lisa, Tanguay, Robert L., Traber, Maret G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4732018/
https://www.ncbi.nlm.nih.gov/pubmed/26774753
http://dx.doi.org/10.1016/j.redox.2016.01.004

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