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Cross-talk between two antioxidants, thioredoxin reductase and heme oxygenase-1, and therapeutic implications for multiple myeloma

Multiple myeloma (MM) is characterized by an accumulation of abnormal clonal plasma cells in the bone marrow. Despite recent advancements in anti-myeloma therapies, MM remains an incurable disease. Antioxidant molecules are upregulated in many cancers, correlating with tumor proliferation, survival,...

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Detalles Bibliográficos
Autores principales: Raninga, Prahlad V., Di Trapani, Giovanna, Vuckovic, Slavica, Tonissen, Kathryn F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4732019/
https://www.ncbi.nlm.nih.gov/pubmed/26795735
http://dx.doi.org/10.1016/j.redox.2016.01.007