Cargando…

Mitochondrial Calcium Uptake Modulates Synaptic Vesicle Endocytosis in Central Nerve Terminals

Presynaptic calcium influx triggers synaptic vesicle (SV) exocytosis and modulates subsequent SV endocytosis. A number of calcium clearance mechanisms are present in central nerve terminals that regulate intracellular free calcium levels both during and after stimulation. During action potential sti...

Descripción completa

Detalles Bibliográficos
Autores principales:	Marland, Jamie Roslin Keynes, Hasel, Philip, Bonnycastle, Katherine, Cousin, Michael Alan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2016
Materias:	Neurobiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4732196/ https://www.ncbi.nlm.nih.gov/pubmed/26644474 http://dx.doi.org/10.1074/jbc.M115.686956

Ejemplares similares

Synaptic vesicle exocytosis and increased cytosolic calcium are both necessary but not sufficient for activity‐dependent bulk endocytosis
por: Morton, Andrew, et al.
Publicado: (2015)

Integration of Synaptic Vesicle Cargo Retrieval with Endocytosis at Central Nerve Terminals
por: Cousin, Michael A.
Publicado: (2017)

Loading a Calcium Dye into Frog Nerve Endings Through the Nerve Stump: Calcium Transient Registration in the Frog Neuromuscular Junction
por: Samigullin, Dmitry V., et al.
Publicado: (2017)

Glycosylation Is Dispensable for Sorting of Synaptotagmin 1 but Is Critical for Targeting of SV2 and Synaptophysin to Recycling Synaptic Vesicles
por: Kwon, Sung E., et al.
Publicado: (2012)

The neuronal protein Neurexin directly interacts with the Scribble–Pix complex to stimulate F-actin assembly for synaptic vesicle clustering
por: Rui, Menglong, et al.
Publicado: (2017)

Pituitary Adenylate Cyclase-activating Polypeptide (PACAP)/PAC(1)HOP1 Receptor Activation Coordinates Multiple Neurotrophic Signaling Pathways: Akt ACTIVATION THROUGH PHOSPHATIDYLINOSITOL 3-KINASE γ AND VESICLE ENDOCYTOSIS FOR NEURONAL SURVIVAL
por: May, Victor, et al.
Publicado: (2010)

Methamphetamine-induced Occludin Endocytosis Is Mediated by the Arp2/3 Complex-regulated Actin Rearrangement
por: Park, Minseon, et al.
Publicado: (2013)

α-Synuclein facilitates endocytosis by elevating the steady-state levels of phosphatidylinositol 4,5-bisphosphate
por: Schechter, Meir, et al.
Publicado: (2021)

γ-Aminobutyric Acid Type A (GABA(A)) Receptor Subunits Play a Direct Structural Role in Synaptic Contact Formation via Their N-terminal Extracellular Domains
por: Brown, Laura E., et al.
Publicado: (2016)

Homeostatic Synaptic Scaling Is Regulated by Protein SUMOylation
por: Craig, Tim J., et al.
Publicado: (2012)

Depolarization-Induced Calcium-Independent Synaptic Vesicle Exo- and Endocytosis at Frog Motor Nerve Terminals
por: Abdrakhmanov, M.M., et al.
Publicado: (2013)

Aph-1 Associates Directly with Full-length and C-terminal Fragments of γ-Secretase Substrates
por: Chen, Allen C., et al.
Publicado: (2010)

The Exosome Secretory Pathway Transports Amyloid Precursor Protein Carboxyl-terminal Fragments from the Cell into the Brain Extracellular Space
por: Perez-Gonzalez, Rocio, et al.
Publicado: (2012)

Calcium Currents Are Enhanced by α(2)δ-1 Lacking Its Membrane Anchor
por: Kadurin, Ivan, et al.
Publicado: (2012)

P2X7 Receptors Trigger ATP Exocytosis and Modify Secretory Vesicle Dynamics in Neuroblastoma Cells
por: Gutiérrez-Martín, Yolanda, et al.
Publicado: (2011)

Extracellular Vesicles Isolated from the Brains of rTg4510 Mice Seed Tau Protein Aggregation in a Threshold-dependent Manner
por: Polanco, Juan Carlos, et al.
Publicado: (2016)

Proinflammatory cytokines induce accumulation of glypican-1-derived heparan sulfate and the C-terminal fragment of β-cleaved APP in autophagosomes of dividing neuronal cells
por: Cheng, Fang, et al.
Publicado: (2020)

Low-density Lipoprotein Receptor-related Proteins in a Novel Mechanism of Axon Guidance and Peripheral Nerve Regeneration
por: Landowski, Lila M., et al.
Publicado: (2016)

Defining a mechanistic link between pigment epithelium–derived factor, docosahexaenoic acid, and corneal nerve regeneration
por: Pham, Thang Luong, et al.
Publicado: (2017)

Botulinum Neurotoxin a Blocks Synaptic Vesicle Exocytosis but Not Endocytosis at the Nerve Terminal
por: Neale, Elaine A., et al.
Publicado: (1999)

Ablation of Vacuole Protein Sorting 18 (Vps18) Gene Leads to Neurodegeneration and Impaired Neuronal Migration by Disrupting Multiple Vesicle Transport Pathways to Lysosomes
por: Peng, Chao, et al.
Publicado: (2012)

DISC1-dependent Regulation of Mitochondrial Dynamics Controls the Morphogenesis of Complex Neuronal Dendrites
por: Norkett, Rosalind, et al.
Publicado: (2016)

The Ubiquitin C-Terminal Hydrolase L1 (UCH-L1) C Terminus Plays a Key Role in Protein Stability, but Its Farnesylation Is Not Required for Membrane Association in Primary Neurons
por: Bishop, Paul, et al.
Publicado: (2014)

The Ca(V)β Subunit Protects the I-II Loop of the Voltage-gated Calcium Channel Ca(V)2.2 from Proteasomal Degradation but Not Oligoubiquitination
por: Page, Karen M., et al.
Publicado: (2016)

Neuritin Up-regulates Kv4.2 α-Subunit of Potassium Channel Expression and Affects Neuronal Excitability by Regulating the Calcium-Calcineurin-NFATc4 Signaling Pathway
por: Yao, Jin-jing, et al.
Publicado: (2016)

Mutations in valosin-containing protein (VCP) decrease ADP/ATP translocation across the mitochondrial membrane and impair energy metabolism in human neurons
por: Ludtmann, Marthe H. R., et al.
Publicado: (2017)

ER stress is not elevated in the 5XFAD mouse model of Alzheimer's disease
por: Sadleir, Katherine R., et al.
Publicado: (2018)

Synaptic Vesicle Recycling Is Unaffected in the Ts65Dn Mouse Model of Down Syndrome
por: Marland, Jamie R. K., et al.
Publicado: (2016)

Control of synaptic vesicle endocytosis by an extracellular signalling molecule
por: Smillie, Karen J., et al.
Publicado: (2013)

Akt/PKB Controls the Activity-Dependent Bulk Endocytosis of Synaptic Vesicles
por: Smillie, Karen J, et al.
Publicado: (2012)

The iTRAPs: Guardians of Synaptic Vesicle Cargo Retrieval During Endocytosis
por: Gordon, Sarah L., et al.
Publicado: (2016)

Proteolytic shedding of the prion protein via activation of metallopeptidase ADAM10 reduces cellular binding and toxicity of amyloid-β oligomers
por: Jarosz-Griffiths, Heledd H., et al.
Publicado: (2019)

Spatial facilitation by a high-performance dragonfly target-detecting neuron
por: Nordström, Karin, et al.
Publicado: (2011)

Importance of Shank3 Protein in Regulating Metabotropic Glutamate Receptor 5 (mGluR5) Expression and Signaling at Synapses
por: Verpelli, Chiara, et al.
Publicado: (2011)

Tumor Necrosis Factor Receptor-associated Factor 6 (TRAF6) Associates with Huntingtin Protein and Promotes Its Atypical Ubiquitination to Enhance Aggregate Formation
por: Zucchelli, Silvia, et al.
Publicado: (2011)

Differentiation of Embryonic Stem Cells into Oligodendrocyte Precursors
por: Jiang, Peng, et al.
Publicado: (2010)

The N Terminus of Monoamine Transporters Is a Lever Required for the Action of Amphetamines
por: Sucic, Sonja, et al.
Publicado: (2010)

Serine 129 Phosphorylation Reduces the Ability of α-Synuclein to Regulate Tyrosine Hydroxylase and Protein Phosphatase 2A in Vitro and in Vivo
por: Lou, Haiyan, et al.
Publicado: (2010)

The Longin SNARE VAMP7/TI-VAMP Adopts a Closed Conformation
por: Vivona, Sandro, et al.
Publicado: (2010)

High Affinity Neurexin Binding to Cell Adhesion G-protein-coupled Receptor CIRL1/Latrophilin-1 Produces an Intercellular Adhesion Complex
por: Boucard, Antony A., et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_6rls9i3tnoem66mqf9qqk2pksu