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Blast phase transformation of chronic myelogenous leukemia presenting with central nervous system manifestation
Chronic myelogenous leukemia (CML) is the most common of all leukemia constituting 15–20% of all leukemia. The clinical course of the diseases runs in two to three phases, initial chronic phase followed by accelerated phase or blast phase. Blast phase most commonly presents clinically as fever, sple...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4732262/ https://www.ncbi.nlm.nih.gov/pubmed/26889299 http://dx.doi.org/10.4103/1793-5482.165778 |
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author | Chikkannaiah, Panduranga Chandranaik, Deepak Devlanaik Erappa, Nagaraj Reddy, Bharat Venkataramappa, Srinivasamurthy |
author_facet | Chikkannaiah, Panduranga Chandranaik, Deepak Devlanaik Erappa, Nagaraj Reddy, Bharat Venkataramappa, Srinivasamurthy |
author_sort | Chikkannaiah, Panduranga |
collection | PubMed |
description | Chronic myelogenous leukemia (CML) is the most common of all leukemia constituting 15–20% of all leukemia. The clinical course of the diseases runs in two to three phases, initial chronic phase followed by accelerated phase or blast phase. Blast phase most commonly presents clinically as fever, splenomegaly, and bone pain. Here, we present a case of CML in blast phase presenting with central nervous system manifestation in a 55-year-old patient with a brief review of the literature. |
format | Online Article Text |
id | pubmed-4732262 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-47322622016-02-17 Blast phase transformation of chronic myelogenous leukemia presenting with central nervous system manifestation Chikkannaiah, Panduranga Chandranaik, Deepak Devlanaik Erappa, Nagaraj Reddy, Bharat Venkataramappa, Srinivasamurthy Asian J Neurosurg Case Report Chronic myelogenous leukemia (CML) is the most common of all leukemia constituting 15–20% of all leukemia. The clinical course of the diseases runs in two to three phases, initial chronic phase followed by accelerated phase or blast phase. Blast phase most commonly presents clinically as fever, splenomegaly, and bone pain. Here, we present a case of CML in blast phase presenting with central nervous system manifestation in a 55-year-old patient with a brief review of the literature. Medknow Publications & Media Pvt Ltd 2016 /pmc/articles/PMC4732262/ /pubmed/26889299 http://dx.doi.org/10.4103/1793-5482.165778 Text en Copyright: © Asian Journal of Neurosurgery http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution NonCommercial ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non commercially, as long as the author is credited and the new creations are licensed under the identical terms. |
spellingShingle | Case Report Chikkannaiah, Panduranga Chandranaik, Deepak Devlanaik Erappa, Nagaraj Reddy, Bharat Venkataramappa, Srinivasamurthy Blast phase transformation of chronic myelogenous leukemia presenting with central nervous system manifestation |
title | Blast phase transformation of chronic myelogenous leukemia presenting with central nervous system manifestation |
title_full | Blast phase transformation of chronic myelogenous leukemia presenting with central nervous system manifestation |
title_fullStr | Blast phase transformation of chronic myelogenous leukemia presenting with central nervous system manifestation |
title_full_unstemmed | Blast phase transformation of chronic myelogenous leukemia presenting with central nervous system manifestation |
title_short | Blast phase transformation of chronic myelogenous leukemia presenting with central nervous system manifestation |
title_sort | blast phase transformation of chronic myelogenous leukemia presenting with central nervous system manifestation |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4732262/ https://www.ncbi.nlm.nih.gov/pubmed/26889299 http://dx.doi.org/10.4103/1793-5482.165778 |
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