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Blast phase transformation of chronic myelogenous leukemia presenting with central nervous system manifestation

Chronic myelogenous leukemia (CML) is the most common of all leukemia constituting 15–20% of all leukemia. The clinical course of the diseases runs in two to three phases, initial chronic phase followed by accelerated phase or blast phase. Blast phase most commonly presents clinically as fever, sple...

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Autores principales: Chikkannaiah, Panduranga, Chandranaik, Deepak Devlanaik, Erappa, Nagaraj, Reddy, Bharat, Venkataramappa, Srinivasamurthy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4732262/
https://www.ncbi.nlm.nih.gov/pubmed/26889299
http://dx.doi.org/10.4103/1793-5482.165778
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author Chikkannaiah, Panduranga
Chandranaik, Deepak Devlanaik
Erappa, Nagaraj
Reddy, Bharat
Venkataramappa, Srinivasamurthy
author_facet Chikkannaiah, Panduranga
Chandranaik, Deepak Devlanaik
Erappa, Nagaraj
Reddy, Bharat
Venkataramappa, Srinivasamurthy
author_sort Chikkannaiah, Panduranga
collection PubMed
description Chronic myelogenous leukemia (CML) is the most common of all leukemia constituting 15–20% of all leukemia. The clinical course of the diseases runs in two to three phases, initial chronic phase followed by accelerated phase or blast phase. Blast phase most commonly presents clinically as fever, splenomegaly, and bone pain. Here, we present a case of CML in blast phase presenting with central nervous system manifestation in a 55-year-old patient with a brief review of the literature.
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spelling pubmed-47322622016-02-17 Blast phase transformation of chronic myelogenous leukemia presenting with central nervous system manifestation Chikkannaiah, Panduranga Chandranaik, Deepak Devlanaik Erappa, Nagaraj Reddy, Bharat Venkataramappa, Srinivasamurthy Asian J Neurosurg Case Report Chronic myelogenous leukemia (CML) is the most common of all leukemia constituting 15–20% of all leukemia. The clinical course of the diseases runs in two to three phases, initial chronic phase followed by accelerated phase or blast phase. Blast phase most commonly presents clinically as fever, splenomegaly, and bone pain. Here, we present a case of CML in blast phase presenting with central nervous system manifestation in a 55-year-old patient with a brief review of the literature. Medknow Publications & Media Pvt Ltd 2016 /pmc/articles/PMC4732262/ /pubmed/26889299 http://dx.doi.org/10.4103/1793-5482.165778 Text en Copyright: © Asian Journal of Neurosurgery http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution NonCommercial ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Case Report
Chikkannaiah, Panduranga
Chandranaik, Deepak Devlanaik
Erappa, Nagaraj
Reddy, Bharat
Venkataramappa, Srinivasamurthy
Blast phase transformation of chronic myelogenous leukemia presenting with central nervous system manifestation
title Blast phase transformation of chronic myelogenous leukemia presenting with central nervous system manifestation
title_full Blast phase transformation of chronic myelogenous leukemia presenting with central nervous system manifestation
title_fullStr Blast phase transformation of chronic myelogenous leukemia presenting with central nervous system manifestation
title_full_unstemmed Blast phase transformation of chronic myelogenous leukemia presenting with central nervous system manifestation
title_short Blast phase transformation of chronic myelogenous leukemia presenting with central nervous system manifestation
title_sort blast phase transformation of chronic myelogenous leukemia presenting with central nervous system manifestation
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4732262/
https://www.ncbi.nlm.nih.gov/pubmed/26889299
http://dx.doi.org/10.4103/1793-5482.165778
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