Haemoglobin degradation underpins the sensitivity of early ring stage Plasmodium falciparum to artemisinins

Current first-line artemisinin antimalarials are threatened by the emergence of resistant Plasmodium falciparum. Decreased sensitivity is evident in the initial (early ring) stage of intraerythrocytic development, meaning that it is crucial to understand the action of artemisinins at this stage. Her...

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Detalles Bibliográficos
Autores principales: Xie, Stanley C., Dogovski, Con, Hanssen, Eric, Chiu, Francis, Yang, Tuo, Crespo, Maria P., Stafford, Che, Batinovic, Steven, Teguh, Silvia, Charman, Susan, Klonis, Nectarios, Tilley, Leann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4732288/
https://www.ncbi.nlm.nih.gov/pubmed/26675237
http://dx.doi.org/10.1242/jcs.178830

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