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A multicenter, non-interventional study to evaluate patient-reported experiences of living with psoriasis

Background: Moderate to severe plaque psoriasis (with or without psoriatic arthritis) places significant burden on patients’ lives. Objective: Explore and document patients’ experiences of living with psoriasis, including symptoms, treatments, impact on daily lives and patient-reported functioning....

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Autores principales: Pariser, David, Schenkel, Brad, Carter, Chureen, Farahi, Kamyar, Brown, T. Michelle, Ellis, Charles N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4732424/
https://www.ncbi.nlm.nih.gov/pubmed/26138406
http://dx.doi.org/10.3109/09546634.2015.1044492
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author Pariser, David
Schenkel, Brad
Carter, Chureen
Farahi, Kamyar
Brown, T. Michelle
Ellis, Charles N.
author_facet Pariser, David
Schenkel, Brad
Carter, Chureen
Farahi, Kamyar
Brown, T. Michelle
Ellis, Charles N.
author_sort Pariser, David
collection PubMed
description Background: Moderate to severe plaque psoriasis (with or without psoriatic arthritis) places significant burden on patients’ lives. Objective: Explore and document patients’ experiences of living with psoriasis, including symptoms, treatments, impact on daily lives and patient-reported functioning. Methods: In a US-based, non-interventional study, narrative interviews were conducted at baseline and again within 16 weeks. In interviews, patients with moderate to severe psoriasis indicated symptoms, ranked symptoms according to level of bother and indicated areas of their lives affected by psoriasis. Transcripts of interviews were coded for themes. Measurements of psoriasis severity including BSA, PGA and PASI were recorded. Results: Symptoms reported most frequently included flaking/scaling (non-scalp areas), itching/scratching and rash, while the most bothersome symptoms were itching/scratching, flaking/scaling (non-scalp areas) and skin pain. Frequently reported impact areas were social and emotional. Conclusion: Broad-reaching interviews with patients with psoriasis show that these patients suffer in many aspects of their lives and in ways not indicated by typical psoriasis severity measures. Patients with psoriatic arthritis reported symptoms and disease-related complications at higher rates than those without arthritis. Physicians’ explorations of the effect of psoriasis on patients’ life events could aid in managing these patients.
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spelling pubmed-47324242016-02-16 A multicenter, non-interventional study to evaluate patient-reported experiences of living with psoriasis Pariser, David Schenkel, Brad Carter, Chureen Farahi, Kamyar Brown, T. Michelle Ellis, Charles N. J Dermatolog Treat Psoriasis & Other Inflammatory Diseases Background: Moderate to severe plaque psoriasis (with or without psoriatic arthritis) places significant burden on patients’ lives. Objective: Explore and document patients’ experiences of living with psoriasis, including symptoms, treatments, impact on daily lives and patient-reported functioning. Methods: In a US-based, non-interventional study, narrative interviews were conducted at baseline and again within 16 weeks. In interviews, patients with moderate to severe psoriasis indicated symptoms, ranked symptoms according to level of bother and indicated areas of their lives affected by psoriasis. Transcripts of interviews were coded for themes. Measurements of psoriasis severity including BSA, PGA and PASI were recorded. Results: Symptoms reported most frequently included flaking/scaling (non-scalp areas), itching/scratching and rash, while the most bothersome symptoms were itching/scratching, flaking/scaling (non-scalp areas) and skin pain. Frequently reported impact areas were social and emotional. Conclusion: Broad-reaching interviews with patients with psoriasis show that these patients suffer in many aspects of their lives and in ways not indicated by typical psoriasis severity measures. Patients with psoriatic arthritis reported symptoms and disease-related complications at higher rates than those without arthritis. Physicians’ explorations of the effect of psoriasis on patients’ life events could aid in managing these patients. Taylor & Francis 2016-01-02 2015-07-03 /pmc/articles/PMC4732424/ /pubmed/26138406 http://dx.doi.org/10.3109/09546634.2015.1044492 Text en © 2015 Janssen Scientific Affairs. Published by Taylor & Francis. http://creativecommons.org/Licenses/by-nc-nd/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License (http://creativecommons.org/Licenses/by-nc-nd/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited, and is not altered, transformed, or built upon in any way.
spellingShingle Psoriasis & Other Inflammatory Diseases
Pariser, David
Schenkel, Brad
Carter, Chureen
Farahi, Kamyar
Brown, T. Michelle
Ellis, Charles N.
A multicenter, non-interventional study to evaluate patient-reported experiences of living with psoriasis
title A multicenter, non-interventional study to evaluate patient-reported experiences of living with psoriasis
title_full A multicenter, non-interventional study to evaluate patient-reported experiences of living with psoriasis
title_fullStr A multicenter, non-interventional study to evaluate patient-reported experiences of living with psoriasis
title_full_unstemmed A multicenter, non-interventional study to evaluate patient-reported experiences of living with psoriasis
title_short A multicenter, non-interventional study to evaluate patient-reported experiences of living with psoriasis
title_sort multicenter, non-interventional study to evaluate patient-reported experiences of living with psoriasis
topic Psoriasis & Other Inflammatory Diseases
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4732424/
https://www.ncbi.nlm.nih.gov/pubmed/26138406
http://dx.doi.org/10.3109/09546634.2015.1044492
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