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Substrate Distortion and the Catalytic Reaction Mechanism of 5-Carboxyvanillate Decarboxylase

[Image: see text] 5-Carboxyvanillate decarboxylase (LigW) catalyzes the conversion of 5-carboxyvanillate to vanillate in the biochemical pathway for the degradation of lignin. This enzyme was shown to require Mn(2+) for catalytic activity and the kinetic constants for the decarboxylation of 5-carbox...

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Detalles Bibliográficos
Autores principales: Vladimirova, Anna, Patskovsky, Yury, Fedorov, Alexander A., Bonanno, Jeffrey B., Fedorov, Elena V., Toro, Rafael, Hillerich, Brandan, Seidel, Ronald D., Richards, Nigel G. J., Almo, Steven C., Raushel, Frank M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2015
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4732527/
https://www.ncbi.nlm.nih.gov/pubmed/26714575
http://dx.doi.org/10.1021/jacs.5b08251

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