A three-dimensional model of the human blood-brain barrier to analyse the transport of nanoparticles and astrocyte/endothelial interactions

The aim of this study was to develop a three-dimensional (3D) model of the human blood-brain barrier in vitro, which mimics the cellular architecture of the CNS and could be used to analyse the delivery of nanoparticles to cells of the CNS. The model includes human astrocytes set in a collagen gel,...

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Detalles Bibliográficos
Autores principales: Sreekanthreddy, Peddagangannagari, Gromnicova, Radka, Davies, Heather, Phillips, James, Romero, Ignacio A., Male, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000Research 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4732555/
https://www.ncbi.nlm.nih.gov/pubmed/26870320
http://dx.doi.org/10.12688/f1000research.7142.2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4732555/
https://www.ncbi.nlm.nih.gov/pubmed/26870320
http://dx.doi.org/10.12688/f1000research.7142.2

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