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Therapeutic Use of 3β-[N-(N′,N′-Dimethylaminoethane) Carbamoyl] Cholesterol-Modified PLGA Nanospheres as Gene Delivery Vehicles for Spinal Cord Injury

Gene delivery holds therapeutic promise for the treatment of neurological diseases and spinal cord injury. Although several studies have investigated the use of non-viral vectors, such as polyethylenimine (PEI), their clinical value is limited by their cytotoxicity. Recently, biodegradable poly (lac...

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Detalles Bibliográficos
Autores principales: Gwak, So-Jung, Yun, Yeomin, Yoon, Do Heum, Kim, Keung Nyun, Ha, Yoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4732605/
https://www.ncbi.nlm.nih.gov/pubmed/26824765
http://dx.doi.org/10.1371/journal.pone.0147389

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