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Susceptibility pattern of uropathogens to ciprofloxacin at the Ghana police hospital

INTRODUCTION: Reports of increasing resistance of uropathogens to antimicrobials is of global concern. Culture and drug susceptibility tests remain a vital guide to effective therapy. The aim of this study was to determine the susceptibility pattern of isolated uropathogens to ciprofloxacin at the G...

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Autores principales: Afriyie, Daniel Kwame, Gyansa-Lutterodt, Martha, Amponsah, Seth Kwabena, Asare, George, Wiredu, Vanessa, Wormenor, Edem, Bugyei, Kwasi Agyei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The African Field Epidemiology Network 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4732620/
https://www.ncbi.nlm.nih.gov/pubmed/26848334
http://dx.doi.org/10.11604/pamj.2015.22.87.6037
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author Afriyie, Daniel Kwame
Gyansa-Lutterodt, Martha
Amponsah, Seth Kwabena
Asare, George
Wiredu, Vanessa
Wormenor, Edem
Bugyei, Kwasi Agyei
author_facet Afriyie, Daniel Kwame
Gyansa-Lutterodt, Martha
Amponsah, Seth Kwabena
Asare, George
Wiredu, Vanessa
Wormenor, Edem
Bugyei, Kwasi Agyei
author_sort Afriyie, Daniel Kwame
collection PubMed
description INTRODUCTION: Reports of increasing resistance of uropathogens to antimicrobials is of global concern. Culture and drug susceptibility tests remain a vital guide to effective therapy. The aim of this study was to determine the susceptibility pattern of isolated uropathogens to ciprofloxacin at the Ghana Police Hospital. METHODS: A total of 705 mid-stream urine samples were collected from patients suspected of having urinary tract infection, and visited the Ghana Police Hospital's laboratory from December 2013 to March 2014. Samples were cultured and isolates identified by standard methods, after which isolates susceptibility to ciprofloxacin was determined. RESULTS: Prevalence of urinary tract infection among patients’ whose samples were analyzed was 15.9%. Predominant uropathogens isolated were E. coli (46.4%), Coliform (41.1%) and Coliform spp. with Candida (6.2%). Other isolates were Pseudomonas spp. (2.7%), Salmonella spp. (1.8%), Candida spp. (0.9%) and Klebsiella spp (0.9%). The overall resistance among the top three isolated uropathogens to ciprofloxacin was 35.9%. Resistance pattern demonstrated by respective isolates to ciprofloxacin were: E. coli (38.5%), Coliform (54.3%), and Coliform spp. with Candida (15%). The other isolates showed 100% sensitivity. CONCLUSION: This study revealed a relatively high ciprofloxacin resistance among isolated uropathogens, hence, the need for prudent prescribing and use of ciprofloxacin in urinary tract infection management.
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spelling pubmed-47326202016-02-04 Susceptibility pattern of uropathogens to ciprofloxacin at the Ghana police hospital Afriyie, Daniel Kwame Gyansa-Lutterodt, Martha Amponsah, Seth Kwabena Asare, George Wiredu, Vanessa Wormenor, Edem Bugyei, Kwasi Agyei Pan Afr Med J Research INTRODUCTION: Reports of increasing resistance of uropathogens to antimicrobials is of global concern. Culture and drug susceptibility tests remain a vital guide to effective therapy. The aim of this study was to determine the susceptibility pattern of isolated uropathogens to ciprofloxacin at the Ghana Police Hospital. METHODS: A total of 705 mid-stream urine samples were collected from patients suspected of having urinary tract infection, and visited the Ghana Police Hospital's laboratory from December 2013 to March 2014. Samples were cultured and isolates identified by standard methods, after which isolates susceptibility to ciprofloxacin was determined. RESULTS: Prevalence of urinary tract infection among patients’ whose samples were analyzed was 15.9%. Predominant uropathogens isolated were E. coli (46.4%), Coliform (41.1%) and Coliform spp. with Candida (6.2%). Other isolates were Pseudomonas spp. (2.7%), Salmonella spp. (1.8%), Candida spp. (0.9%) and Klebsiella spp (0.9%). The overall resistance among the top three isolated uropathogens to ciprofloxacin was 35.9%. Resistance pattern demonstrated by respective isolates to ciprofloxacin were: E. coli (38.5%), Coliform (54.3%), and Coliform spp. with Candida (15%). The other isolates showed 100% sensitivity. CONCLUSION: This study revealed a relatively high ciprofloxacin resistance among isolated uropathogens, hence, the need for prudent prescribing and use of ciprofloxacin in urinary tract infection management. The African Field Epidemiology Network 2015-10-01 /pmc/articles/PMC4732620/ /pubmed/26848334 http://dx.doi.org/10.11604/pamj.2015.22.87.6037 Text en © Daniel Kwame Afriyie et al. http://creativecommons.org/licenses/by/2.0/ The Pan African Medical Journal - ISSN 1937-8688. This is an Open Access article distributed under the terms of the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research
Afriyie, Daniel Kwame
Gyansa-Lutterodt, Martha
Amponsah, Seth Kwabena
Asare, George
Wiredu, Vanessa
Wormenor, Edem
Bugyei, Kwasi Agyei
Susceptibility pattern of uropathogens to ciprofloxacin at the Ghana police hospital
title Susceptibility pattern of uropathogens to ciprofloxacin at the Ghana police hospital
title_full Susceptibility pattern of uropathogens to ciprofloxacin at the Ghana police hospital
title_fullStr Susceptibility pattern of uropathogens to ciprofloxacin at the Ghana police hospital
title_full_unstemmed Susceptibility pattern of uropathogens to ciprofloxacin at the Ghana police hospital
title_short Susceptibility pattern of uropathogens to ciprofloxacin at the Ghana police hospital
title_sort susceptibility pattern of uropathogens to ciprofloxacin at the ghana police hospital
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4732620/
https://www.ncbi.nlm.nih.gov/pubmed/26848334
http://dx.doi.org/10.11604/pamj.2015.22.87.6037
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