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Susceptibility pattern of uropathogens to ciprofloxacin at the Ghana police hospital
INTRODUCTION: Reports of increasing resistance of uropathogens to antimicrobials is of global concern. Culture and drug susceptibility tests remain a vital guide to effective therapy. The aim of this study was to determine the susceptibility pattern of isolated uropathogens to ciprofloxacin at the G...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The African Field Epidemiology Network
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4732620/ https://www.ncbi.nlm.nih.gov/pubmed/26848334 http://dx.doi.org/10.11604/pamj.2015.22.87.6037 |
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author | Afriyie, Daniel Kwame Gyansa-Lutterodt, Martha Amponsah, Seth Kwabena Asare, George Wiredu, Vanessa Wormenor, Edem Bugyei, Kwasi Agyei |
author_facet | Afriyie, Daniel Kwame Gyansa-Lutterodt, Martha Amponsah, Seth Kwabena Asare, George Wiredu, Vanessa Wormenor, Edem Bugyei, Kwasi Agyei |
author_sort | Afriyie, Daniel Kwame |
collection | PubMed |
description | INTRODUCTION: Reports of increasing resistance of uropathogens to antimicrobials is of global concern. Culture and drug susceptibility tests remain a vital guide to effective therapy. The aim of this study was to determine the susceptibility pattern of isolated uropathogens to ciprofloxacin at the Ghana Police Hospital. METHODS: A total of 705 mid-stream urine samples were collected from patients suspected of having urinary tract infection, and visited the Ghana Police Hospital's laboratory from December 2013 to March 2014. Samples were cultured and isolates identified by standard methods, after which isolates susceptibility to ciprofloxacin was determined. RESULTS: Prevalence of urinary tract infection among patients’ whose samples were analyzed was 15.9%. Predominant uropathogens isolated were E. coli (46.4%), Coliform (41.1%) and Coliform spp. with Candida (6.2%). Other isolates were Pseudomonas spp. (2.7%), Salmonella spp. (1.8%), Candida spp. (0.9%) and Klebsiella spp (0.9%). The overall resistance among the top three isolated uropathogens to ciprofloxacin was 35.9%. Resistance pattern demonstrated by respective isolates to ciprofloxacin were: E. coli (38.5%), Coliform (54.3%), and Coliform spp. with Candida (15%). The other isolates showed 100% sensitivity. CONCLUSION: This study revealed a relatively high ciprofloxacin resistance among isolated uropathogens, hence, the need for prudent prescribing and use of ciprofloxacin in urinary tract infection management. |
format | Online Article Text |
id | pubmed-4732620 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | The African Field Epidemiology Network |
record_format | MEDLINE/PubMed |
spelling | pubmed-47326202016-02-04 Susceptibility pattern of uropathogens to ciprofloxacin at the Ghana police hospital Afriyie, Daniel Kwame Gyansa-Lutterodt, Martha Amponsah, Seth Kwabena Asare, George Wiredu, Vanessa Wormenor, Edem Bugyei, Kwasi Agyei Pan Afr Med J Research INTRODUCTION: Reports of increasing resistance of uropathogens to antimicrobials is of global concern. Culture and drug susceptibility tests remain a vital guide to effective therapy. The aim of this study was to determine the susceptibility pattern of isolated uropathogens to ciprofloxacin at the Ghana Police Hospital. METHODS: A total of 705 mid-stream urine samples were collected from patients suspected of having urinary tract infection, and visited the Ghana Police Hospital's laboratory from December 2013 to March 2014. Samples were cultured and isolates identified by standard methods, after which isolates susceptibility to ciprofloxacin was determined. RESULTS: Prevalence of urinary tract infection among patients’ whose samples were analyzed was 15.9%. Predominant uropathogens isolated were E. coli (46.4%), Coliform (41.1%) and Coliform spp. with Candida (6.2%). Other isolates were Pseudomonas spp. (2.7%), Salmonella spp. (1.8%), Candida spp. (0.9%) and Klebsiella spp (0.9%). The overall resistance among the top three isolated uropathogens to ciprofloxacin was 35.9%. Resistance pattern demonstrated by respective isolates to ciprofloxacin were: E. coli (38.5%), Coliform (54.3%), and Coliform spp. with Candida (15%). The other isolates showed 100% sensitivity. CONCLUSION: This study revealed a relatively high ciprofloxacin resistance among isolated uropathogens, hence, the need for prudent prescribing and use of ciprofloxacin in urinary tract infection management. The African Field Epidemiology Network 2015-10-01 /pmc/articles/PMC4732620/ /pubmed/26848334 http://dx.doi.org/10.11604/pamj.2015.22.87.6037 Text en © Daniel Kwame Afriyie et al. http://creativecommons.org/licenses/by/2.0/ The Pan African Medical Journal - ISSN 1937-8688. This is an Open Access article distributed under the terms of the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Afriyie, Daniel Kwame Gyansa-Lutterodt, Martha Amponsah, Seth Kwabena Asare, George Wiredu, Vanessa Wormenor, Edem Bugyei, Kwasi Agyei Susceptibility pattern of uropathogens to ciprofloxacin at the Ghana police hospital |
title | Susceptibility pattern of uropathogens to ciprofloxacin at the Ghana police hospital |
title_full | Susceptibility pattern of uropathogens to ciprofloxacin at the Ghana police hospital |
title_fullStr | Susceptibility pattern of uropathogens to ciprofloxacin at the Ghana police hospital |
title_full_unstemmed | Susceptibility pattern of uropathogens to ciprofloxacin at the Ghana police hospital |
title_short | Susceptibility pattern of uropathogens to ciprofloxacin at the Ghana police hospital |
title_sort | susceptibility pattern of uropathogens to ciprofloxacin at the ghana police hospital |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4732620/ https://www.ncbi.nlm.nih.gov/pubmed/26848334 http://dx.doi.org/10.11604/pamj.2015.22.87.6037 |
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