Sphingosine-1-Phosphate Induces Dose-Dependent Chemotaxis or Fugetaxis of T-ALL Blasts through S1P1 Activation

Sphingosine-1-phosphate (S1P) is a bioactive sphingolipid involved in several physiological processes including cell migration and differentiation. S1P signaling is mediated through five G protein-coupled receptors (S1P1-S1P5). S1P1 is crucial to the exit of T-lymphocytes from the thymus and periphe...

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Detalles Bibliográficos
Autores principales: Messias, Carolina V., Santana-Van-Vliet, Eliane, Lemos, Julia P., Moreira, Otacilio C., Cotta-de-Almeida, Vinicius, Savino, Wilson, Mendes-da-Cruz, Daniella Arêas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4732661/
https://www.ncbi.nlm.nih.gov/pubmed/26824863
http://dx.doi.org/10.1371/journal.pone.0148137

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