Three-Dimensional Imaging of the Intracellular Fate of Plasmid DNA and Transgene Expression: ZsGreen1 and Tissue Clearing Method CUBIC Are an Optimal Combination for Multicolor Deep Imaging in Murine Tissues

Evaluation methods for determining the distribution of transgene expression in the body and the in vivo fate of viral and non-viral vectors are necessary for successful development of in vivo gene delivery systems. Here, we evaluated the spatial distribution of transgene expression using tissue clea...

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Detalles Bibliográficos
Autores principales: Fumoto, Shintaro, Nishimura, Koyo, Nishida, Koyo, Kawakami, Shigeru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4732687/
https://www.ncbi.nlm.nih.gov/pubmed/26824850
http://dx.doi.org/10.1371/journal.pone.0148233

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4732687/
https://www.ncbi.nlm.nih.gov/pubmed/26824850
http://dx.doi.org/10.1371/journal.pone.0148233

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