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The Succinate Receptor GPR91 Is Involved in Pressure Overload-Induced Ventricular Hypertrophy
BACKGROUND: Pulmonary arterial hypertension is characterized by increased pressure overload that leads to right ventricular hypertrophy (RVH). GPR91 is a formerly orphan G-protein-coupled receptor (GPCR) that has been characterized as a receptor for succinate; however, its role in RVH remains unknow...
Autores principales: | Yang, Lei, Yu, Di, Mo, Ran, Zhang, Jiru, Hua, Hu, Hu, Liang, Feng, Yu, Wang, Song, Zhang, Wei-yan, Yin, Ning, Mo, Xu-Ming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4732750/ https://www.ncbi.nlm.nih.gov/pubmed/26824665 http://dx.doi.org/10.1371/journal.pone.0147597 |
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