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Long-Term Persistence of Bi-functionality Contributes to the Robustness of Microbial Life through Exaptation
Modern enzymes are highly optimized biocatalysts that process their substrates with extreme efficiency. Many enzymes catalyze more than one reaction; however, the persistence of such ambiguities, their consequences and evolutionary causes are largely unknown. As a paradigmatic case, we study the his...
Autores principales: | Plach, Maximilian G., Reisinger, Bernd, Sterner, Reinhard, Merkl, Rainer |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4732765/ https://www.ncbi.nlm.nih.gov/pubmed/26824644 http://dx.doi.org/10.1371/journal.pgen.1005836 |
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