Cargando…

AMP-Activated Protein Kinase Regulates Oxidative Metabolism in Caenorhabditis elegans through the NHR-49 and MDT-15 Transcriptional Regulators

Cellular energy regulation relies on complex signaling pathways that respond to fuel availability and metabolic demands. Dysregulation of these networks is implicated in the development of human metabolic diseases such as obesity and metabolic syndrome. In Caenorhabditis elegans the AMP-activated pr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Moreno-Arriola, Elizabeth, EL Hafidi, Mohammed, Ortega-Cuéllar, Daniel, Carvajal, Karla
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4732773/ https://www.ncbi.nlm.nih.gov/pubmed/26824904 http://dx.doi.org/10.1371/journal.pone.0148089

Ejemplares similares

Litchi flower essential oil balanced lipid metabolism through the regulation of DAF-2/IIS, MDT-15/SBP-1, and MDT-15/NHR-49 pathway
por: Chen, Yun, et al.
Publicado: (2022)

Nuclear hormone receptor NHR-49 is an essential regulator of stress resilience and healthy aging in Caenorhabditis elegans
por: Doering, Kelsie R. S., et al.
Publicado: (2023)

The Caenorhabditis elegans Oxidative Stress Response Requires the NHR-49 Transcription Factor
por: Hu, Queenie, et al.
Publicado: (2018)

Nuclear receptor signaling via NHR-49/MDT-15 regulates stress resilience and proteostasis in response to reproductive and metabolic cues
por: Sala, Ambre J., et al.
Publicado: (2023)

NHR-49 Transcription Factor Regulates Immunometabolic Response and Survival of Caenorhabditis elegans during Enterococcus faecalis Infection
por: Dasgupta, Madhumanti, et al.
Publicado: (2020)

Fat-lowering effects of isorhamnetin are via NHR-49-dependent pathway in Caenorhabditis elegans
por: Farias-Pereira, Renalison, et al.
Publicado: (2019)

Gain-of-Function Alleles in Caenorhabditis elegans Nuclear Hormone Receptor nhr-49 Are Functionally Distinct
por: Lee, Kayoung, et al.
Publicado: (2016)

The Role of Nuclear Receptor NHR-64 in Fat Storage Regulation in Caenorhabditis elegans
por: Liang, Bin, et al.
Publicado: (2010)

Nuclear hormone receptor NHR-49 acts in parallel with HIF-1 to promote hypoxia adaptation in Caenorhabditis elegans
por: Doering, Kelsie RS, et al.
Publicado: (2022)

Quantitative proteomics by amino acid labeling identifies novel NHR-49 regulated proteins in C. elegans
por: Fredens, Julius, et al.
Publicado: (2012)

Nuclear receptors NHR-49 and NHR-79 promote peroxisome proliferation to compensate for aldehyde dehydrogenase deficiency in C. elegans
por: Zeng, Lidan, et al.
Publicado: (2021)

NHR-23 and SPE-44 regulate distinct sets of genes during Caenorhabditis elegans spermatogenesis
por: Ragle, James Matthew, et al.
Publicado: (2022)

Pasteurized Akkermansia muciniphila Reduces Fat Accumulation via nhr-49-Mediated Nuclear Hormone Signaling Pathway in Caenorhabditis elegans
por: Wu, Zhongqin, et al.
Publicado: (2022)

Correction to: NHR-23 and SPE-44 regulate distinct sets of genes during Caenorhabditis elegans spermatogenesis
Publicado: (2023)

The ω‐3 fatty acid α‐linolenic acid extends Caenorhabditis elegans lifespan via NHR‐49/PPARα and oxidation to oxylipins
por: Qi, Wenbo, et al.
Publicado: (2017)

Ilex paraguariensis modulates fat metabolism in Caenorhabditis elegans through purinergic system (ADOR-1) and nuclear hormone receptor (NHR-49) pathways
por: Machado, Marina Lopes, et al.
Publicado: (2018)

The conserved Mediator subunit MDT-15 is required for oxidative stress responses in Caenorhabditis elegans
por: Goh, Grace Y S, et al.
Publicado: (2014)

Dietary Restriction Induced Longevity Is Mediated by Nuclear Receptor NHR-62 in Caenorhabditis elegans
por: Heestand, Bree N., et al.
Publicado: (2013)

Nuclear Hormone Receptor NHR-49 Controls Fat Consumption and Fatty Acid Composition in C. elegans
por: Gilst, Marc R. Van, et al.
Publicado: (2005)

Lipid-lowering fibrates extend C. elegans lifespan in a NHR-49/PPARalpha-dependent manner
por: Brandstädt, Sven, et al.
Publicado: (2013)

The MDT-15 Subunit of Mediator Interacts with Dietary Restriction to Modulate Longevity and Fluoranthene Toxicity in Caenorhabditis elegans
por: Schleit, Jennifer, et al.
Publicado: (2011)

Mediator subunit MDT-15/MED15 and Nuclear Receptor HIZR-1/HNF4 cooperate to regulate toxic metal stress responses in Caenorhabditis elegans
por: Shomer, Naomi, et al.
Publicado: (2019)

Germline Signals Deploy NHR-49 to Modulate Fatty-Acid β-Oxidation and Desaturation in Somatic Tissues of C. elegans
por: Ratnappan, Ramesh, et al.
Publicado: (2014)

Antioxidant Baccharis trimera Leaf Extract Suppresses Lipid Accumulation in C. elegans Dependent on Transcription Factor NHR-49
por: Souza, Flávia Roberta Monteiro, et al.
Publicado: (2022)

The Caenorhabditis elegans HNF4α Homolog, NHR-31, Mediates Excretory Tube Growth and Function through Coordinate Regulation of the Vacuolar ATPase
por: Hahn-Windgassen, Annett, et al.
Publicado: (2009)

Caenorhabditis elegans NHR-14/HNF4α regulates DNA damage-induced apoptosis through cooperating with cep-1/p53
por: Sang, Lei, et al.
Publicado: (2022)

Cell nonautonomous roles of NHR‐49 in promoting longevity and innate immunity
por: Naim, Nikki, et al.
Publicado: (2021)

Mediator subunit MDT-15 promotes expression of propionic acid breakdown genes to prevent embryonic lethality in Caenorhabditis elegans
por: Goh, Grace Ying Shyen, et al.
Publicado: (2023)

The tailless Ortholog nhr-67 Regulates Patterning of Gene Expression and Morphogenesis in the C. elegans Vulva
por: Fernandes, Jolene S, et al.
Publicado: (2007)

NHR-49/PPAR-α and HLH-30/TFEB cooperate for C. elegans host defense via a flavin-containing monooxygenase
por: Wani, Khursheed A, et al.
Publicado: (2021)

Caenorhabditis elegans: A Useful Model for Studying Metabolic Disorders in Which Oxidative Stress Is a Contributing Factor
por: Moreno-Arriola, Elizabeth, et al.
Publicado: (2014)

Allosteric regulation of C. elegans AMP-activated protein kinase
por: Scanlon, Daniel M, et al.
Publicado: (2022)

NHR‐49/HNF4 integrates regulation of fatty acid metabolism with a protective transcriptional response to oxidative stress and fasting
por: Goh, Grace Y. S., et al.
Publicado: (2018)

Sumoylated NHR-25/NR5A Regulates Cell Fate during C. elegans Vulval Development
por: Ward, Jordan D., et al.
Publicado: (2013)

PIM-Related Kinases Selectively Regulate Olfactory Sensations in Caenorhabditis elegans
por: Kalichamy, Karunambigai S., et al.
Publicado: (2019)

MDT-28/PLIN-1 mediates lipid droplet-microtubule interaction via DLC-1 in Caenorhabditis elegans
por: Xie, Kang, et al.
Publicado: (2019)

Regulation of metabolism in Caenorhabditis elegans longevity
por: Gallo, Marco, et al.
Publicado: (2010)

A novel kinase regulates dietary restriction-mediated longevity in Caenorhabditis elegans
por: Chamoli, Manish, et al.
Publicado: (2014)

The nuclear hormone receptor NHR-86 controls anti-pathogen responses in C. elegans
por: Peterson, Nicholas D., et al.
Publicado: (2019)

Specificity of DNA-binding by the FAX-1 and NHR-67 nuclear receptors of Caenorhabditis elegans is partially mediated via a subclass-specific P-box residue
por: DeMeo, Stephen D, et al.
Publicado: (2008)

Cannot write session to /tmp/vufind_sessions/sess_bqi9a2a3s11ita0n1dtjgq81oa