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TGF-β(2) induces epithelial-mesenchymal transition in cultured human lens epithelial cells through activation of the PI3K/Akt/mTOR signaling pathway

The present study aimed to investigate whether the phosphatidylinositol 3-kinase (PI3K)/protein kinase B (Akt)/mammalian target of rapamycin (mTOR) signaling pathway is involved in the transforming growth factor β(2) (TGF-β(2))-induced epithelial-mesenchymal transition (EMT) in human lens epithelial...

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Detalles Bibliográficos
Autores principales: GUO, RUI, MENG, QIANLI, GUO, HAIKE, XIAO, LIJIA, YANG, XIAOHONG, CUI, YING, HUANG, YU
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4732853/
https://www.ncbi.nlm.nih.gov/pubmed/26647778
http://dx.doi.org/10.3892/mmr.2015.4645