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In-Silico Computing of the Most Deleterious nsSNPs in HBA1 Gene
BACKGROUND: α-Thalassemia (α-thal) is a genetic disorder caused by the substitution of single amino acid or large deletions in the HBA1 and/or HBA2 genes. METHOD: Using modern bioinformatics tools as a systematic in-silico approach to predict the deleterious SNPs in the HBA1 gene and its significant...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4733110/ https://www.ncbi.nlm.nih.gov/pubmed/26824843 http://dx.doi.org/10.1371/journal.pone.0147702 |