Cargando…

Therapy with natalizumab is associated with high JCV seroconversion and rising JCV index values

OBJECTIVE: The aim of the study was to analyze John Cunningham virus (JCV) serology in natalizumab-treated patients over time and assess whether they are influenced by natalizumab treatment. METHODS: German (n = 1,921; 525 longitudinally) and French (n = 1,259; 711 longitudinally) patients were asse...

Descripción completa

Detalles Bibliográficos
Autores principales:	Schwab, Nicholas, Schneider-Hohendorf, Tilman, Pignolet, Béatrice, Breuer, Johanna, Gross, Catharina C., Göbel, Kerstin, Brassat, David, Wiendl, Heinz
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4733149/ https://www.ncbi.nlm.nih.gov/pubmed/26848486 http://dx.doi.org/10.1212/NXI.0000000000000195

Ejemplares similares

High rates of JCV seroconversion in a large international cohort of natalizumab-treated patients
por: Dwyer, Christopher M., et al.
Publicado: (2021)

Rising JCV-Ab index during natalizumab therapy for MS: Inauspicious for a highly efficacious drug
por: Javed, Adil, et al.
Publicado: (2016)

JCV seroconversion rate during the SARS COVID-19 pandemic
por: Vigiser, I., et al.
Publicado: (2022)

Natalizumab Affects T-Cell Phenotype in Multiple Sclerosis: Implications for JCV Reactivation
por: Iannetta, Marco, et al.
Publicado: (2016)

Anti-JCV antibody index does not change during ocrelizumab-treatment
por: Rempe, Torge, et al.
Publicado: (2020)

JC Polyomavirus (JCV) and Monoclonal Antibodies: Friends or Potential Foes?
por: Diotti, Roberta Antonia, et al.
Publicado: (2013)

Dynamic changes of MMP-9 plasma levels correlate with JCV reactivation and immune activation in natalizumab-treated multiple sclerosis patients
por: Iannetta, Marco, et al.
Publicado: (2019)

Longitudinal analyses of anti-JCV antibody index for risk assessment of progressive multifocal leukoencephalopathy
por: Salmen, A., et al.
Publicado: (2016)

Bag3-Induced Autophagy Is Associated with Degradation of JCV Oncoprotein, T-Ag
por: Sariyer, Ilker Kudret, et al.
Publicado: (2012)

No detection of EBV, BKV and JCV in breast cancer tissue samples in Iran
por: Dowran, Razieh, et al.
Publicado: (2019)

Impact of Disease-Modifying Treatments on the Longitudinal Evolution of Anti-JCV Antibody Index in Multiple Sclerosis
por: Hegen, Harald, et al.
Publicado: (2018)

Primary bilateral adrenal B-cell lymphoma associated with EBV and JCV infection
por: Barzon, Luisa, et al.
Publicado: (2009)

JC Virus Encephalopathy Is Associated with a Novel Agnoprotein-Deletion JCV Variant
por: Dang, Xin, et al.
Publicado: (2012)

Changes to anti-JCV antibody levels in a Swedish national MS cohort
por: Warnke, Clemens, et al.
Publicado: (2013)

Encephalitis with coinfection by Jamestown canyon virus (JCV) and varicella zoster virus (VZV)
por: VanderVeen, Nathan, et al.
Publicado: (2020)

Statistical analysis of PML incidences of natalizumab-treated patients from 2009 to 2016: outcomes after introduction of the Stratify JCV® DxSelect™ antibody assay
por: Campagnolo, Denise, et al.
Publicado: (2016)

Stability and predictive value of anti-JCV antibody index in multiple sclerosis: A 6-year longitudinal study
por: Hegen, Harald, et al.
Publicado: (2017)

Human JCV Infections as a Bio-Anthropological Marker of the Formation of Brazilian Amazonian Populations
por: Cayres-Vallinoto, Izaura M. V., et al.
Publicado: (2012)

Activation of c-Myc and Cyclin D1 by JCV T-Antigen and β-Catenin in Colon Cancer
por: Ripple, Michael J., et al.
Publicado: (2014)

Neural Crest Cells Isolated from the Bone Marrow of Transgenic Mice Express JCV T-Antigen
por: Gordon, Jennifer, et al.
Publicado: (2013)

Assessment of immune functions and MRI disease activity in relapsing-remitting multiple sclerosis patients switching from natalizumab to fingolimod (ToFingo-Successor)
por: Klotz, Luisa, et al.
Publicado: (2015)

Pur-Alpha Induces JCV Gene Expression and Viral Replication by Suppressing SRSF1 in Glial Cells
por: Sariyer, Ilker Kudret, et al.
Publicado: (2016)

JCV viruria associates with suboptimal recovery of kidney function three years after living kidney donation
por: Querido, Sara, et al.
Publicado: (2022)

Association between hMLH1 hypermethylation and JC virus (JCV) infection in human colorectal cancer (CRC)
por: Vilkin, Alex, et al.
Publicado: (2010)

Viral tumor antigen expression is no longer required in radiation-resistant subpopulation of JCV induced mouse medulloblastoma cells
por: Donadoni, Martina, et al.
Publicado: (2018)

Prevalence of Anti-JC Virus (JCV) Antibodies in the Multiple Sclerosis (MS) Population in Cyprus: A Retrospective Study
por: Lambrianides, Sakis, et al.
Publicado: (2019)

Trafficking of lymphocytes into the CNS
por: Schwab, Nicholas, et al.
Publicado: (2015)

Definition and characterization of novel HLA-*A02-restricted CD8(+) T cell epitopes derived from JCV polyomavirus with clinical relevance
por: Mani, Jiju, et al.
Publicado: (2016)

Immune Cell Profiling During Switching from Natalizumab to Fingolimod Reveals Differential Effects on Systemic Immune-Regulatory Networks and on Trafficking of Non-T Cell Populations into the Cerebrospinal Fluid—Results from the ToFingo Successor Study
por: Lohmann, Lisa, et al.
Publicado: (2018)

VLA-4 blockade promotes differential routes into human CNS involving PSGL-1 rolling of T cells and MCAM-adhesion of T(H)17 cells
por: Schneider-Hohendorf, Tilman, et al.
Publicado: (2014)

Targeting MCAM for next-generation modulation of leucocyte trafficking
por: Schneider-Hohendorf, Tilman, et al.
Publicado: (2023)

Enhanced pathogenicity of Th17 cells due to natalizumab treatment: Implications for MS disease rebound
por: Janoschka, Claudia, et al.
Publicado: (2022)

Temporal Pattern of ICAM-I Mediated Regulatory T Cell Recruitment to Sites of Inflammation in Adoptive Transfer Model of Multiple Sclerosis
por: Doerck, Sebastian, et al.
Publicado: (2010)

Ineffective treatment of PML with pembrolizumab: Exhausted memory T-cell subsets as a clue?
por: Pawlitzki, Marc, et al.
Publicado: (2019)

MCAM/CD146 Signaling via PLCγ1 Leads to Activation of β(1)-Integrins in Memory T-Cells Resulting in Increased Brain Infiltration
por: Zondler, Lisa, et al.
Publicado: (2020)

Broader Epstein–Barr virus–specific T cell receptor repertoire in patients with multiple sclerosis
por: Schneider-Hohendorf, Tilman, et al.
Publicado: (2022)

Correction: Broader Epstein–Barr virus–specific T cell receptor repertoire in patients with multiple sclerosis
por: Schneider-Hohendorf, Tilman, et al.
Publicado: (2022)

High anti-JCPyV serum titers coincide with high CSF cell counts in RRMS patients
por: Schneider-Hohendorf, Tilman, et al.
Publicado: (2020)

Serum Neurofilament Levels and PML Risk in Patients With Multiple Sclerosis Treated With Natalizumab
por: Fissolo, Nicolás, et al.
Publicado: (2021)

Blockade of MCAM/CD146 impedes CNS infiltration of T cells over the choroid plexus
por: Breuer, Johanna, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_ggtar9425s6vb927n49p4mqdco