Role of Serologic and Molecular Diagnostic Assays in Identification and Management of Hepatitis C Virus Infection

The drugs available for the treatment of hepatitis C virus (HCV) have evolved to provide shorter treatment duration and higher rates of sustained virologic response (SVR), and the role of HCV infection diagnostic tests has had to evolve in order to meet changing clinical needs. This review gives an...

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Autores principales: Cloherty, Gavin, Talal, Andrew, Coller, Kelly, Steinhart, Corklin, Hackett, John, Dawson, George, Rockstroh, Juergen, Feld, Jordan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2016
Materias:
Minireviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4733206/
https://www.ncbi.nlm.nih.gov/pubmed/26659219
http://dx.doi.org/10.1128/JCM.02407-15
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author Cloherty, Gavin
Talal, Andrew
Coller, Kelly
Steinhart, Corklin
Hackett, John
Dawson, George
Rockstroh, Juergen
Feld, Jordan
author_facet Cloherty, Gavin
Talal, Andrew
Coller, Kelly
Steinhart, Corklin
Hackett, John
Dawson, George
Rockstroh, Juergen
Feld, Jordan
author_sort Cloherty, Gavin
collection PubMed
description The drugs available for the treatment of hepatitis C virus (HCV) have evolved to provide shorter treatment duration and higher rates of sustained virologic response (SVR), and the role of HCV infection diagnostic tests has had to evolve in order to meet changing clinical needs. This review gives an overview on the role of HCV infection diagnostic testing (molecular and serological tools) used in the diagnosis and management of HCV infection. All of this critical information guides physician decisions to optimize patient clinical outcomes. Also discussed is the future direction of diagnostic testing in the context of further advances in drug development.
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spelling pubmed-47332062016-02-13 Role of Serologic and Molecular Diagnostic Assays in Identification and Management of Hepatitis C Virus Infection Cloherty, Gavin Talal, Andrew Coller, Kelly Steinhart, Corklin Hackett, John Dawson, George Rockstroh, Juergen Feld, Jordan J Clin Microbiol Minireviews The drugs available for the treatment of hepatitis C virus (HCV) have evolved to provide shorter treatment duration and higher rates of sustained virologic response (SVR), and the role of HCV infection diagnostic tests has had to evolve in order to meet changing clinical needs. This review gives an overview on the role of HCV infection diagnostic testing (molecular and serological tools) used in the diagnosis and management of HCV infection. All of this critical information guides physician decisions to optimize patient clinical outcomes. Also discussed is the future direction of diagnostic testing in the context of further advances in drug development. American Society for Microbiology 2016-01-28 2016-02 /pmc/articles/PMC4733206/ /pubmed/26659219 http://dx.doi.org/10.1128/JCM.02407-15 Text en Copyright © 2016 Cloherty et al. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license (http://creativecommons.org/licenses/by/4.0/) .
spellingShingle Minireviews
Cloherty, Gavin
Talal, Andrew
Coller, Kelly
Steinhart, Corklin
Hackett, John
Dawson, George
Rockstroh, Juergen
Feld, Jordan
Role of Serologic and Molecular Diagnostic Assays in Identification and Management of Hepatitis C Virus Infection
title Role of Serologic and Molecular Diagnostic Assays in Identification and Management of Hepatitis C Virus Infection
title_full Role of Serologic and Molecular Diagnostic Assays in Identification and Management of Hepatitis C Virus Infection
title_fullStr Role of Serologic and Molecular Diagnostic Assays in Identification and Management of Hepatitis C Virus Infection
title_full_unstemmed Role of Serologic and Molecular Diagnostic Assays in Identification and Management of Hepatitis C Virus Infection
title_short Role of Serologic and Molecular Diagnostic Assays in Identification and Management of Hepatitis C Virus Infection
title_sort role of serologic and molecular diagnostic assays in identification and management of hepatitis c virus infection
topic Minireviews
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4733206/
https://www.ncbi.nlm.nih.gov/pubmed/26659219
http://dx.doi.org/10.1128/JCM.02407-15
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