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International consensus on ANA patterns (ICAP): the bumpy road towards a consensus on reporting ANA results
The International Consensus on ANA Patterns (ICAP) was initiated as a workshop aiming to thoroughly discuss and achieve consensus regarding the morphological patterns observed in the indirect immunofluorescence assay on HEp-2 cells. One of the topics discussed at the second ICAP workshop, and addres...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4733811/ https://www.ncbi.nlm.nih.gov/pubmed/26831867 http://dx.doi.org/10.1007/s13317-016-0075-0 |
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author | Damoiseaux, Jan von Mühlen, Carlos A. Garcia-De La Torre, Ignacio Carballo, Orlando Gabriel de Melo Cruvinel, Wilson Francescantonio, Paulo Luiz Carvalho Fritzler, Marvin J. Herold, Manfred Mimori, Tsuneyo Satoh, Minoru Andrade, Luis E. C. Chan, Edward K. L. Conrad, Karsten |
author_facet | Damoiseaux, Jan von Mühlen, Carlos A. Garcia-De La Torre, Ignacio Carballo, Orlando Gabriel de Melo Cruvinel, Wilson Francescantonio, Paulo Luiz Carvalho Fritzler, Marvin J. Herold, Manfred Mimori, Tsuneyo Satoh, Minoru Andrade, Luis E. C. Chan, Edward K. L. Conrad, Karsten |
author_sort | Damoiseaux, Jan |
collection | PubMed |
description | The International Consensus on ANA Patterns (ICAP) was initiated as a workshop aiming to thoroughly discuss and achieve consensus regarding the morphological patterns observed in the indirect immunofluorescence assay on HEp-2 cells. One of the topics discussed at the second ICAP workshop, and addressed in this paper, was the harmonization of reporting ANA test results. This discussion centered on the issue if cytoplasmic and mitotic patterns should be reported as positive or negative. This report outlines the issues that impact on two major different reporting methods. Although it was appreciated by all participants that cytoplasmic and mitotic patterns are clinically relevant, implications for existing diagnostic/classification criteria for ANA-associated diseases in particular hampered a final consensus on this topic. Evidently, a more concerted action of all relevant stakeholders is required. Future ICAP workshops may help to facilitate this action. |
format | Online Article Text |
id | pubmed-4733811 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Springer International Publishing |
record_format | MEDLINE/PubMed |
spelling | pubmed-47338112016-02-05 International consensus on ANA patterns (ICAP): the bumpy road towards a consensus on reporting ANA results Damoiseaux, Jan von Mühlen, Carlos A. Garcia-De La Torre, Ignacio Carballo, Orlando Gabriel de Melo Cruvinel, Wilson Francescantonio, Paulo Luiz Carvalho Fritzler, Marvin J. Herold, Manfred Mimori, Tsuneyo Satoh, Minoru Andrade, Luis E. C. Chan, Edward K. L. Conrad, Karsten Auto Immun Highlights Original Article The International Consensus on ANA Patterns (ICAP) was initiated as a workshop aiming to thoroughly discuss and achieve consensus regarding the morphological patterns observed in the indirect immunofluorescence assay on HEp-2 cells. One of the topics discussed at the second ICAP workshop, and addressed in this paper, was the harmonization of reporting ANA test results. This discussion centered on the issue if cytoplasmic and mitotic patterns should be reported as positive or negative. This report outlines the issues that impact on two major different reporting methods. Although it was appreciated by all participants that cytoplasmic and mitotic patterns are clinically relevant, implications for existing diagnostic/classification criteria for ANA-associated diseases in particular hampered a final consensus on this topic. Evidently, a more concerted action of all relevant stakeholders is required. Future ICAP workshops may help to facilitate this action. Springer International Publishing 2016-01-30 /pmc/articles/PMC4733811/ /pubmed/26831867 http://dx.doi.org/10.1007/s13317-016-0075-0 Text en © The Author(s) 2016 |
spellingShingle | Original Article Damoiseaux, Jan von Mühlen, Carlos A. Garcia-De La Torre, Ignacio Carballo, Orlando Gabriel de Melo Cruvinel, Wilson Francescantonio, Paulo Luiz Carvalho Fritzler, Marvin J. Herold, Manfred Mimori, Tsuneyo Satoh, Minoru Andrade, Luis E. C. Chan, Edward K. L. Conrad, Karsten International consensus on ANA patterns (ICAP): the bumpy road towards a consensus on reporting ANA results |
title | International consensus on ANA patterns (ICAP): the bumpy road towards a consensus on reporting ANA results |
title_full | International consensus on ANA patterns (ICAP): the bumpy road towards a consensus on reporting ANA results |
title_fullStr | International consensus on ANA patterns (ICAP): the bumpy road towards a consensus on reporting ANA results |
title_full_unstemmed | International consensus on ANA patterns (ICAP): the bumpy road towards a consensus on reporting ANA results |
title_short | International consensus on ANA patterns (ICAP): the bumpy road towards a consensus on reporting ANA results |
title_sort | international consensus on ana patterns (icap): the bumpy road towards a consensus on reporting ana results |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4733811/ https://www.ncbi.nlm.nih.gov/pubmed/26831867 http://dx.doi.org/10.1007/s13317-016-0075-0 |
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