Digging deep into “dirty” drugs – modulation of the methylation machinery

DNA methylation and histone modification are epigenetic mechanisms that result in altered gene expression and cellular phenotype. The exact role of methylation in myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML) remains unclear. However, aberrations (e.g. loss-/gain-of-function or up...

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Detalles Bibliográficos
Autores principales: Pleyer, Lisa, Greil, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Informa Healthcare 2015
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4733942/
https://www.ncbi.nlm.nih.gov/pubmed/25566693
http://dx.doi.org/10.3109/03602532.2014.995379

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4733942/
https://www.ncbi.nlm.nih.gov/pubmed/25566693
http://dx.doi.org/10.3109/03602532.2014.995379

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