Facile synthesis of 4H-chromene derivatives via base-mediated annulation of ortho-hydroxychalcones and 2-bromoallyl sulfones

The cesium carbonate-mediated reaction of 2-bromoallyl sulfones and ortho-hydroxychalcones furnished 3-arylsulfonyl-4H-chromene derivatives in 58–67% yield (18 examples). 2-Bromoallyl sulfones functioned as synthetic surrogates for allenyl sulfones in the reaction.

Detalles Bibliográficos
Autores principales: Thadkapally, Srinivas, Kunjachan, Athira C, Menon, Rajeev S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2016
Materias:
Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4734429/
https://www.ncbi.nlm.nih.gov/pubmed/26877804
http://dx.doi.org/10.3762/bjoc.12.3
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author Thadkapally, Srinivas
Kunjachan, Athira C
Menon, Rajeev S
author_facet Thadkapally, Srinivas
Kunjachan, Athira C
Menon, Rajeev S
author_sort Thadkapally, Srinivas
collection PubMed
description The cesium carbonate-mediated reaction of 2-bromoallyl sulfones and ortho-hydroxychalcones furnished 3-arylsulfonyl-4H-chromene derivatives in 58–67% yield (18 examples). 2-Bromoallyl sulfones functioned as synthetic surrogates for allenyl sulfones in the reaction.
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spelling pubmed-47344292016-02-12 Facile synthesis of 4H-chromene derivatives via base-mediated annulation of ortho-hydroxychalcones and 2-bromoallyl sulfones Thadkapally, Srinivas Kunjachan, Athira C Menon, Rajeev S Beilstein J Org Chem Letter The cesium carbonate-mediated reaction of 2-bromoallyl sulfones and ortho-hydroxychalcones furnished 3-arylsulfonyl-4H-chromene derivatives in 58–67% yield (18 examples). 2-Bromoallyl sulfones functioned as synthetic surrogates for allenyl sulfones in the reaction. Beilstein-Institut 2016-01-06 /pmc/articles/PMC4734429/ /pubmed/26877804 http://dx.doi.org/10.3762/bjoc.12.3 Text en Copyright © 2016, Thadkapally et al. https://creativecommons.org/licenses/by/2.0https://www.beilstein-journals.org/bjoc/termsThis is an Open Access article under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The license is subject to the Beilstein Journal of Organic Chemistry terms and conditions: (https://www.beilstein-journals.org/bjoc/terms)
spellingShingle Letter
Thadkapally, Srinivas
Kunjachan, Athira C
Menon, Rajeev S
Facile synthesis of 4H-chromene derivatives via base-mediated annulation of ortho-hydroxychalcones and 2-bromoallyl sulfones
title Facile synthesis of 4H-chromene derivatives via base-mediated annulation of ortho-hydroxychalcones and 2-bromoallyl sulfones
title_full Facile synthesis of 4H-chromene derivatives via base-mediated annulation of ortho-hydroxychalcones and 2-bromoallyl sulfones
title_fullStr Facile synthesis of 4H-chromene derivatives via base-mediated annulation of ortho-hydroxychalcones and 2-bromoallyl sulfones
title_full_unstemmed Facile synthesis of 4H-chromene derivatives via base-mediated annulation of ortho-hydroxychalcones and 2-bromoallyl sulfones
title_short Facile synthesis of 4H-chromene derivatives via base-mediated annulation of ortho-hydroxychalcones and 2-bromoallyl sulfones
title_sort facile synthesis of 4h-chromene derivatives via base-mediated annulation of ortho-hydroxychalcones and 2-bromoallyl sulfones
topic Letter
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4734429/
https://www.ncbi.nlm.nih.gov/pubmed/26877804
http://dx.doi.org/10.3762/bjoc.12.3
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