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Effectiveness of Meningococcal B Vaccine against Endemic Hypervirulent Neisseria meningitidis W Strain, England

Serum samples from children immunized with a meningococcal serogroup B vaccine demonstrated potent serum bactericidal antibody activity against the hypervirulent Neisseria meningitidis serogroup W strain circulating in England. The recent introduction of this vaccine into the United Kingdom national...

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Detalles Bibliográficos
Autores principales: Ladhani, Shamez N., Giuliani, Marzia Monica, Biolchi, Alessia, Pizza, Mariagrazia, Beebeejaun, Kazim, Lucidarme, Jay, Findlow, Jamie, Ramsay, Mary E., Borrow, Ray
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4734511/
https://www.ncbi.nlm.nih.gov/pubmed/26811872
http://dx.doi.org/10.3201/eid2202.150369
Descripción
Sumario:Serum samples from children immunized with a meningococcal serogroup B vaccine demonstrated potent serum bactericidal antibody activity against the hypervirulent Neisseria meningitidis serogroup W strain circulating in England. The recent introduction of this vaccine into the United Kingdom national immunization program should also help protect infants against this endemic strain.