Bordetella pertussis Strain Lacking Pertactin and Pertussis Toxin

A Bordetella pertussis strain lacking 2 acellular vaccine immunogens, pertussis toxin and pertactin, was isolated from an unvaccinated infant in New York State in 2013. Comparison with a French strain that was pertussis toxin–deficient, pertactin wild-type showed that the strains carry the same 28-k...

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Detalles Bibliográficos
Autores principales: Williams, Margaret M., Sen, Kathryn, Weigand, Michael R., Skoff, Tami H., Cunningham, Victoria A., Halse, Tanya A., Tondella, M. Lucia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2016
Materias:
Dispatch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4734536/
https://www.ncbi.nlm.nih.gov/pubmed/26812174
http://dx.doi.org/10.3201/eid2202.151332
Descripción
Sumario:A Bordetella pertussis strain lacking 2 acellular vaccine immunogens, pertussis toxin and pertactin, was isolated from an unvaccinated infant in New York State in 2013. Comparison with a French strain that was pertussis toxin–deficient, pertactin wild-type showed that the strains carry the same 28-kb deletion in similar genomes.

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