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Microevolution of Outbreak-Associated Middle East Respiratory Syndrome Coronavirus, South Korea, 2015
During the 2015 Middle East respiratory syndrome coronavirus outbreak in South Korea, we sequenced full viral genomes of strains isolated from 4 patients early and late during infection. Patients represented at least 4 generations of transmission. We found no evidence of changes in the evolutionary...
Autores principales: | , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Centers for Disease Control and Prevention
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4734539/ https://www.ncbi.nlm.nih.gov/pubmed/26814649 http://dx.doi.org/10.3201/eid2202.151700 |
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author | Seong, Moon-Woo Kim, So Yeon Corman, Victor Max Kim, Taek Soo Cho, Sung Im Kim, Man Jin Lee, Seung Jun Lee, Jee-Soo Seo, Soo Hyun Ahn, Ji Soo Yu, Byeong Su Park, Nare Oh, Myoung-don Park, Wan Beom Lee, Ji Yeon Kim, Gayeon Joh, Joon Sung Jeong, Ina Kim, Eui Chong Drosten, Christian Park, Sung Sup |
author_facet | Seong, Moon-Woo Kim, So Yeon Corman, Victor Max Kim, Taek Soo Cho, Sung Im Kim, Man Jin Lee, Seung Jun Lee, Jee-Soo Seo, Soo Hyun Ahn, Ji Soo Yu, Byeong Su Park, Nare Oh, Myoung-don Park, Wan Beom Lee, Ji Yeon Kim, Gayeon Joh, Joon Sung Jeong, Ina Kim, Eui Chong Drosten, Christian Park, Sung Sup |
author_sort | Seong, Moon-Woo |
collection | PubMed |
description | During the 2015 Middle East respiratory syndrome coronavirus outbreak in South Korea, we sequenced full viral genomes of strains isolated from 4 patients early and late during infection. Patients represented at least 4 generations of transmission. We found no evidence of changes in the evolutionary rate and no reason to suspect adaptive changes in viral proteins. |
format | Online Article Text |
id | pubmed-4734539 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Centers for Disease Control and Prevention |
record_format | MEDLINE/PubMed |
spelling | pubmed-47345392016-02-11 Microevolution of Outbreak-Associated Middle East Respiratory Syndrome Coronavirus, South Korea, 2015 Seong, Moon-Woo Kim, So Yeon Corman, Victor Max Kim, Taek Soo Cho, Sung Im Kim, Man Jin Lee, Seung Jun Lee, Jee-Soo Seo, Soo Hyun Ahn, Ji Soo Yu, Byeong Su Park, Nare Oh, Myoung-don Park, Wan Beom Lee, Ji Yeon Kim, Gayeon Joh, Joon Sung Jeong, Ina Kim, Eui Chong Drosten, Christian Park, Sung Sup Emerg Infect Dis Dispatch During the 2015 Middle East respiratory syndrome coronavirus outbreak in South Korea, we sequenced full viral genomes of strains isolated from 4 patients early and late during infection. Patients represented at least 4 generations of transmission. We found no evidence of changes in the evolutionary rate and no reason to suspect adaptive changes in viral proteins. Centers for Disease Control and Prevention 2016-02 /pmc/articles/PMC4734539/ /pubmed/26814649 http://dx.doi.org/10.3201/eid2202.151700 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited. |
spellingShingle | Dispatch Seong, Moon-Woo Kim, So Yeon Corman, Victor Max Kim, Taek Soo Cho, Sung Im Kim, Man Jin Lee, Seung Jun Lee, Jee-Soo Seo, Soo Hyun Ahn, Ji Soo Yu, Byeong Su Park, Nare Oh, Myoung-don Park, Wan Beom Lee, Ji Yeon Kim, Gayeon Joh, Joon Sung Jeong, Ina Kim, Eui Chong Drosten, Christian Park, Sung Sup Microevolution of Outbreak-Associated Middle East Respiratory Syndrome Coronavirus, South Korea, 2015 |
title | Microevolution of Outbreak-Associated Middle East Respiratory Syndrome Coronavirus, South Korea, 2015 |
title_full | Microevolution of Outbreak-Associated Middle East Respiratory Syndrome Coronavirus, South Korea, 2015 |
title_fullStr | Microevolution of Outbreak-Associated Middle East Respiratory Syndrome Coronavirus, South Korea, 2015 |
title_full_unstemmed | Microevolution of Outbreak-Associated Middle East Respiratory Syndrome Coronavirus, South Korea, 2015 |
title_short | Microevolution of Outbreak-Associated Middle East Respiratory Syndrome Coronavirus, South Korea, 2015 |
title_sort | microevolution of outbreak-associated middle east respiratory syndrome coronavirus, south korea, 2015 |
topic | Dispatch |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4734539/ https://www.ncbi.nlm.nih.gov/pubmed/26814649 http://dx.doi.org/10.3201/eid2202.151700 |
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