Nanopore Sequencing as a Rapidly Deployable Ebola Outbreak Tool

Rapid sequencing of RNA/DNA from pathogen samples obtained during disease outbreaks provides critical scientific and public health information. However, challenges exist for exporting samples to laboratories or establishing conventional sequencers in remote outbreak regions. We successfully used a n...

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Detalles Bibliográficos
Autores principales: Hoenen, Thomas, Groseth, Allison, Rosenke, Kyle, Fischer, Robert J., Hoenen, Andreas, Judson, Seth D., Martellaro, Cynthia, Falzarano, Darryl, Marzi, Andrea, Squires, R. Burke, Wollenberg, Kurt R., de Wit, Emmie, Prescott, Joseph, Safronetz, David, van Doremalen, Neeltje, Bushmaker, Trenton, Feldmann, Friederike, McNally, Kristin, Bolay, Fatorma K., Fields, Barry, Sealy, Tara, Rayfield, Mark, Nichol, Stuart T., Zoon, Kathryn C., Massaquoi, Moses, Munster, Vincent J., Feldmann, Heinz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2016
Materias:
Dispatch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4734547/
https://www.ncbi.nlm.nih.gov/pubmed/26812583
http://dx.doi.org/10.3201/eid2202.151796
Descripción
Sumario:Rapid sequencing of RNA/DNA from pathogen samples obtained during disease outbreaks provides critical scientific and public health information. However, challenges exist for exporting samples to laboratories or establishing conventional sequencers in remote outbreak regions. We successfully used a novel, pocket-sized nanopore sequencer at a field diagnostic laboratory in Liberia during the current Ebola virus outbreak.

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