Apoptosis and antitumor effects induced by the combination of an mTOR inhibitor and an autophagy inhibitor in human osteosarcoma MG63 cells

The inhibition of the mammalian target of rapamycin (mTOR) signaling pathway promotes the initiation of autophagy. Although it remains under debate whether chemotherapy-induced autophagy in tumor cells is a protective response or is invoked to promote cell death, recent studies indicate that autopha...

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Detalles Bibliográficos
Autores principales: HORIE, RYOSUKE, NAKAMURA, OSAMU, YAMAGAMI, YOSHIKI, MORI, MASAKI, NISHIMURA, HIDEKI, FUKUOKA, NATSUKO, YAMAMOTO, TETSUJI
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4734606/
https://www.ncbi.nlm.nih.gov/pubmed/26530936
http://dx.doi.org/10.3892/ijo.2015.3227

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4734606/
https://www.ncbi.nlm.nih.gov/pubmed/26530936
http://dx.doi.org/10.3892/ijo.2015.3227

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