Cargando…
Induction of Cell Death in Growing Human T-Cells and Cell Survival in Resting Cells in Response to the Human T-Cell Leukemia Virus Type 1 Tax
Tax1 encoded by the human T-cell leukemia virus type 1 (HTLV-1) has been believed to dysregulate the expression of cellular genes involved in cell survival and mortality, leading to the development of adult T-cell leukemia (ATL). The function of Tax1 in ATL development however is still controversial...
Autores principales: | Mizuguchi, Mariko, Sasaki, Yuka, Hara, Toshifumi, Higuchi, Masaya, Tanaka, Yuetsu, Funato, Noriko, Tanaka, Nobuyuki, Fujii, Masahiro, Nakamura, Masataka |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4734616/ https://www.ncbi.nlm.nih.gov/pubmed/26829041 http://dx.doi.org/10.1371/journal.pone.0148217 |
Ejemplares similares
-
Human T-cell leukemia virus type-I Tax induces the expression of CD83 on T cells
por: Tanaka, Yuetsu, et al.
Publicado: (2015) -
Downregulation of proapoptotic Bim augments IL-2-independent T-cell transformation by human T-cell leukemia virus type-1 Tax
por: Higuchi, Masaya, et al.
Publicado: (2014) -
HTLV-1 Tax-activated NF-κB is involved in both cell growth and death
por: Mizuguchi, Mariko, et al.
Publicado: (2014) -
Human T-cell leukemia virus type 2 Tax protein induces interleukin 2-independent growth in a T-cell line
por: Kondo, Rie, et al.
Publicado: (2006) -
Promoter CpG methylation inhibits Krüppel-like factor 2 (KLF2)-Mediated repression of hTERT gene expression in human T-cells
por: Mizuguchi, Mariko, et al.
Publicado: (2021)