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Metronomic Doses of Temozolomide Enhance the Efficacy of Carbon Nanotube CpG Immunotherapy in an Invasive Glioma Model
Even when treated with aggressive current therapies, most patients with glioblastoma survive less than two years. Rapid tumor growth, an invasive nature, and the blood-brain barrier, which limits the penetration of large molecules into the brain, all contribute to the poor tumor response associated...
Autores principales: | Ouyang, Mao, White, Ethan E., Ren, Hui, Guo, Qin, Zhang, Ian, Gao, Hang, Yanyan, Song, Chen, Xuebo, Weng, Yiming, Da Fonseca, Anna, Shah, Sunny, Manuel, Edwin R., Zhang, Leying, Vonderfecht, Steven L., Alizadeh, Darya, Berlin, Jacob M., Badie, Behnam |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4734656/ https://www.ncbi.nlm.nih.gov/pubmed/26829221 http://dx.doi.org/10.1371/journal.pone.0148139 |
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