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ClassTR: Classifying Within-Host Heterogeneity Based on Tandem Repeats with Application to Mycobacterium tuberculosis Infections
Genomic tools have revealed genetically diverse pathogens within some hosts. Within-host pathogen diversity, which we refer to as “complex infection”, is increasingly recognized as a determinant of treatment outcome for infections like tuberculosis. Complex infection arises through two mechanisms: w...
Autores principales: | Chindelevitch, Leonid, Colijn, Caroline, Moodley, Prashini, Wilson, Douglas, Cohen, Ted |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4734664/ https://www.ncbi.nlm.nih.gov/pubmed/26829497 http://dx.doi.org/10.1371/journal.pcbi.1004475 |
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