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Effect of 3′UTR RET Variants on RET mRNA Secondary Structure and Disease Presentation in Medullary Thyroid Carcinoma

BACKGROUND: The RET S836S variant has been associated with early onset and increased risk for metastatic disease in medullary thyroid carcinoma (MTC). However, the mechanism by which this variant modulates MTC pathogenesis is still open to discuss. Of interest, strong linkage disequilibrium (LD) bet...

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Detalles Bibliográficos
Autores principales:	Ceolin, Lucieli, Romitti, Mirian, Rodrigues Siqueira, Débora, Vaz Ferreira, Carla, Oliboni Scapineli, Jessica, Assis-Brazil, Beatriz, Vieira Maximiano, Rodolfo, Dias Amarante, Tauanne, de Souza Nunes, Miriam Celi, Weber, Gerald, Maia, Ana Luiza
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4734678/ https://www.ncbi.nlm.nih.gov/pubmed/26829565 http://dx.doi.org/10.1371/journal.pone.0147840

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